111900-33-5 Usage
General Description
(1R,3R)-1-aminocyclopentane-1,3-dicarboxylic acid is a compound with the chemical formula C7H11NO4. It is a biologically important molecule that acts as an agonist of the metabotropic glutamate receptor 8 (mGluR8). This receptor is a potential target for the treatment of various neurological disorders, including anxiety, depression, and schizophrenia. The compound's unique 1R,3R stereochemistry confers specific pharmacological properties, making it a valuable tool for studying the functioning of mGluR8 and potentially developing new therapeutic drugs. Additionally, its structure and properties make it a useful probe for investigating the physiological and pathological roles of glutamate receptors in the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 111900-33-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,9,0 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 111900-33:
(8*1)+(7*1)+(6*1)+(5*9)+(4*0)+(3*0)+(2*3)+(1*3)=75
75 % 10 = 5
So 111900-33-5 is a valid CAS Registry Number.
111900-33-5Relevant articles and documents
Carbamate-directed hydroboration: Enantioselective synthesis of the excitatory amino acid 1-aminocyclopentane-1,3-dicarboxylic acid
Hodgson, David M.,Thompson, Alison J.,Wadman, Sjoerd
, p. 3357 - 3358 (2007/10/03)
Carbamate-directed hydroboration (using BH3) of 1-substituted 3- cyclopentenes 2, 6 and 9 and an enantioselective synthesis of the excitatory amine acid 1-aminocyclopentane-1,3-dicarboxylic acid via carbamate-directed asymmetric hydroboration [90% de, 45% ee using (+)-IpcBH2] of cyclopentene 2 are described.
CHEMOENZYMATIC SYNTHESIS OF CONFORMATIONALLY RIGID GLUTAMIC ACID ANALOGUES
Trigalo, F.,Buisson, D.,Azerad, R.
, p. 6109 - 6112 (2007/10/02)
All stereomers of cyclohexane cyclopentane-derived analogues of glutamic acid have been synthesized from the corresponding 3-keto-cycloalkyl carboxylic acid esters by a combination of microbial steps and standard chemical methods.
