89253-38-3 Usage
Description
(1R,3S)-ACPD, also known as 1-aminocyclopentane-1,3-dicarboxylic acid, is a synthetic chemical compound that acts as an agonist for specific subtypes of glutamate receptors in the brain. Structurally similar to the neurotransmitter glutamate, it has been utilized in research to explore the physiological and pharmacological impacts of glutamate receptors. (1R,3S)-ACPD exhibits excitatory effects on neurons and aids in the investigation of the role of glutamate receptors in neurological processes such as learning and memory. Furthermore, it has been considered for potential therapeutic applications in conditions like epilepsy and neurodegenerative diseases, making it a significant tool in neuroscience research for elucidating the functions and mechanisms of glutamate receptors in the brain.
Uses
Used in Neuroscience Research:
(1R,3S)-ACPD is used as a research tool for studying the physiological and pharmacological effects of glutamate receptors. It helps in understanding the role of these receptors in various neurological processes, including learning and memory.
Used in Neurological Process Investigation:
(1R,3S)-ACPD is used as an excitatory agent for neurons to investigate the involvement of glutamate receptors in cognitive functions and memory enhancement.
Used in Therapeutic Research for Neurological Conditions:
(1R,3S)-ACPD is used as a potential therapeutic agent in the study and treatment of conditions such as epilepsy and neurodegenerative diseases, aiming to explore its efficacy in managing or alleviating symptoms associated with these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 89253-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,2,5 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 89253-38:
(7*8)+(6*9)+(5*2)+(4*5)+(3*3)+(2*3)+(1*8)=163
163 % 10 = 3
So 89253-38-3 is a valid CAS Registry Number.
89253-38-3Relevant articles and documents
Carbamate-directed hydroboration: Enantioselective synthesis of the excitatory amino acid 1-aminocyclopentane-1,3-dicarboxylic acid
Hodgson, David M.,Thompson, Alison J.,Wadman, Sjoerd
, p. 3357 - 3358 (2007/10/03)
Carbamate-directed hydroboration (using BH3) of 1-substituted 3- cyclopentenes 2, 6 and 9 and an enantioselective synthesis of the excitatory amine acid 1-aminocyclopentane-1,3-dicarboxylic acid via carbamate-directed asymmetric hydroboration [90% de, 45% ee using (+)-IpcBH2] of cyclopentene 2 are described.
CHEMOENZYMATIC SYNTHESIS OF CONFORMATIONALLY RIGID GLUTAMIC ACID ANALOGUES
Trigalo, F.,Buisson, D.,Azerad, R.
, p. 6109 - 6112 (2007/10/02)
All stereomers of cyclohexane cyclopentane-derived analogues of glutamic acid have been synthesized from the corresponding 3-keto-cycloalkyl carboxylic acid esters by a combination of microbial steps and standard chemical methods.
