111964-19-3Relevant academic research and scientific papers
ASYMMETRIC SYNTHESIS XII: STEREOCONTROLLED ELECTROPHILIC-NUCLEOPHILIC α,α'-SUBSTITUTION OF THE PYRROLIDINE RING.
Arseniyadis, S.,Huang, P. Q.,Piveteau, D.,Husson, H.-P.
, p. 2457 - 2470 (2007/10/02)
The synthesis of 2-cyano-5-oxazolopyrrolidine 3, a chiral pyrrolidine synthon, is described.Conditions were established that permitted sequential chemoselective reactions at the C-2 aminonitrile (electrophilic substitution) and at the C-5 aminoether (nucl
ASYMMETRIC SYNTHESIS X : A CHIRAL PYRROLIDINE SYNTHON FOR A NEW APPROACH TO THE SYNTHESIS OF ALKALOIDS
Huang, P. Q.,Arseniyadis, S.,Husson, H. -P.
, p. 547 - 550 (2007/10/02)
The synthesis of chiral 2-cyano-5-oxazolopyrrolidine 3 is reported.The synthesis of the optically pure ant venom alkaloid, (+)-(S)-trans-2-heptyl-5-butyl-pyrrolidine 7, has been achieved from 3.
