1119899-37-4

Basic information

• Product Name: 7-cyanobenzo[b]thiophen-2-ylboronic acid
• Synonyms: 7-cyanobenzo[b]thiophen-2-ylboronic acid;Boronic acid, B-(7-cyanobenzo[b]thien-2-yl)-
• CAS NO: 1119899-37-4
• Molecular Formula: C₉H₆BNO₂S
• Molecular Weight: 203.02544
• Mol File: 1119899-37-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 474.9±48.0 °C(Predicted)
• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 6.35±0.30(Predicted)
• CAS DataBase Reference: 7-cyanobenzo[b]thiophen-2-ylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-cyanobenzo[b]thiophen-2-ylboronic acid(1119899-37-4)
• EPA Substance Registry System: 7-cyanobenzo[b]thiophen-2-ylboronic acid(1119899-37-4)

Safety Data

• Hazardous Substances Data: 1119899-37-4(Hazardous Substances Data)

Usage

General Description

7-cyanobenzo[b]thiophen-2-ylboronic acid is a chemical compound with the molecular formula C8H6BNO2S. It belongs to the class of boronic acids and is derived from benzo[b]thiophene. 7-cyanobenzo[b]thiophen-2-ylboronic acid is used as a building block in organic synthesis and medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. It is also utilized in the synthesis of biologically active molecules and serves as a key intermediate in the creation of various chemical compounds. 7-cyanobenzo[b]thiophen-2-ylboronic acid possesses versatile reactivity and has attracted attention in the scientific and industrial communities for its potential applications in diverse fields.

Upstream product

• 17347-34-1 benzo[b]thiophene-4-carbonitrile 
• 22780-71-8 benzo[b]thiophene-7-carbonitrile 

Downstream Products

• 1138473-59-2 2-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)-5-methylpyrimidin-4-yl)benzo[b]thiophene-7-carbonitrile 

Relevant articles and documents

PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS

Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.