112014-67-2

Upstream product

• 107438-62-0 (1R,2R,3R,5S)-2-Bromo-3-hydroxy-7,7-dimethyl-bicyclo[3.2.0]heptan-6-one 
• 57709-02-1 (+/-)-2-exo-bromo-3-endo-hydroxy-7,7-dimethylbicyclo<3.2.0>heptan-6-one 
• 767-85-1 (+/-)-7,7-dimethylbicyclo<3.2.0>hept-2-en-6-one 
• 100853-07-4 (+/-)-3-endo-hydroxy-7,7-dimethylbicyclo<3.2.0>heptan-6-one 
• 65-85-0 benzoic acid 
• 100898-02-0 (+)-(1R,5S)-7,7-dimethylbicyclo<3.2.0>hept-2-en-6-one 
• 100853-06-3 (1R,5S,6S)-7,7-dimethylbicyclo<3.2.0>hept-2-en-6-endo-ol 
• 100853-07-4 (1R,3S,5S)-3-hydroxy-7,7-dimethylbicyclo<3.2.0>heptan-6-one 

Relevant academic research and scientific papers

Resolution of 7,7-Dimethylbicyclohept-2-en-6-one using Mortierella ramanniana and 3α,20β-Hydroxy-steroid Dehydrogenase, Photochemistry of 3-Hydroxy-7,7-dimethylbicycloheptan-6-ones, and the Synthesis of (+)-Eldanolide

The fungus Mortierella ramanniana reduced 7,7-dimethylbicyclohept-2-en-6-one (1) to give the (6S)-endo-alcohol (9) and the (6S)-exo-alcohol (10).In contrast the enzyme 3α,20β-hydroxy-steroid dehydrogenase was found to give the (6S)-endo-alcohol (9)