767-85-1Relevant academic research and scientific papers
Carbocyclic Analogues of Penicillin
Meth-Cohn, Otto,Reason, Andrew J.,Roberts, Stanley M.
, p. 90 - 92 (1982)
The synthesis of the title systems is described by cycloaddition of dimethylketen to cyclopentadiene, addition of hypobromous acid to the product and use of a nitrile-mediated rearrangement to give 4-cyano-6-exo-benzyloxy-3,3-dimethylbicycloheptan-2-one (5b) and its derivatives by further modification.
Synthesis of (3S,4R)-Eldanolide and (5S,12R)-Leukotriene-B4 through Photolysis of Optically Active Hydroxy-7,7-dimethylbicycloheptanones
Davies, H. Geoff,Roberts, Stanley M.,Wakefield, Basil J.,Winders, John A.
, p. 1166 - 1168 (2007/10/02)
Photoisomerisation of 3-hydroxy-7,7-dimethylbicycloheptan-6-ones is the key step in a new route to the pheromone eldanolide while leukotriene-B4 is available through a photolytic retro reaction of 2-hydroxy-7,7-dimethylbicycloheptan-6-ones.
