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"3'-O-(2-cyanoethoxy(diisopropylamino)phosphino)-6-N,2'-O-dibenzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine" is a complex organic compound with a molecular formula of C51H52N6O9P. It is a modified adenosine derivative, which is a nucleoside composed of adenine and ribose. The compound features a 3'-O-(2-cyanoethoxy(diisopropylamino)phosphino) group, which is a protecting group used in the synthesis of oligonucleotides. The 6-N,2'-O-dibenzoyl groups are also protecting groups, while the 5'-O-(4,4'-dimethoxytrityl) group is a common protecting group used in solid-phase synthesis. The 2',3'-secoadenosine part refers to the presence of a carbon-carbon bond between the 2' and 3' positions of the ribose sugar, making it a 2',3'-secoadenosine derivative. 3'-O-(2-cyanoethoxy(diisopropylamino)phosphino)-6-N,2'-O-dibenzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine is used in the synthesis of modified nucleic acids and has potential applications in the development of new drugs and therapeutics.

1120329-52-3

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1120329-52-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1120329-52-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,0,3,2 and 9 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1120329-52:
(9*1)+(8*1)+(7*2)+(6*0)+(5*3)+(4*2)+(3*9)+(2*5)+(1*2)=93
93 % 10 = 3
So 1120329-52-3 is a valid CAS Registry Number.

1120329-52-3Downstream Products

1120329-52-3Relevant academic research and scientific papers

UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability

Langkjaer, Niels,Pasternak, Anna,Wengel, Jesper

experimental part, p. 5420 - 5425 (2009/12/06)

UNA (unlocked nucleic acid) monomers are acyclic derivatives of RNA lacking the C2′-C3′-bond of the ribose ring of RNA. Synthesis of phosphoramidite UNA building blocks of the nucleobases adenine, cytosine, guanine, and uracil is described herein together

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