1120329-51-2

Upstream product

• 1044505-21-6 6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine 
• 98-88-4 benzoyl chloride 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 4546-55-8 N-benzoyladenosine 
• 129666-75-7 6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine 

Downstream Products

• 1120329-52-3 3'-O-(2-cyanoethoxy(diisopropylamino)phosphino)-6-N,2'-O-dibenzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-secoadenosine 

Relevant academic research and scientific papers

UNA AMIDITES AND USES THEREOF

Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a disease which utilize a composition or

UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability

UNA (unlocked nucleic acid) monomers are acyclic derivatives of RNA lacking the C2′-C3′-bond of the ribose ring of RNA. Synthesis of phosphoramidite UNA building blocks of the nucleobases adenine, cytosine, guanine, and uracil is described herein together