112082-42-5

Upstream product

• 28819-05-8 (S)-2-benzyloxycarbonylamino-propionic acid methyl ester 
• 149-73-5 trimethyl orthoformate 
• 1142-20-7 N-Cbz-Ala 
• 82353-55-7 benzyl (S)-1-oxopropan-2-ylcarbamate 
• 501-53-1 benzyl chloroformate 
• 67-56-1 methanol 

Downstream Products

• 113283-76-4 [(S)-1-((4R,6R)-4,6-Dimethyl-[1,3]dioxan-2-yl)-ethyl]-carbamic acid benzyl ester 
• 113283-73-1 [(S)-1-((4S,6S)-4,6-Dimethyl-[1,3]dioxan-2-yl)-ethyl]-carbamic acid benzyl ester 
• 113283-62-8 (S)-benzyl (1-(1,3-dioxan-2-yl)ethyl)carbamate 
• 299207-22-0 benzyl 1-(1,3-dioxolan-2-yl)ethylcarbamate 
• 113350-29-1 [(1S,2S)-2-((1R,3R)-3-Hydroxy-1-methyl-butoxy)-1-methyl-pent-4-enyl]-carbamic acid benzyl ester 
• 113350-23-5 [(1S,2S)-2-((1S,3S)-3-Hydroxy-1-methyl-butoxy)-1-methyl-pent-4-enyl]-carbamic acid benzyl ester 
• 113283-79-7 [(1S,2R)-2-((1R,3R)-3-Hydroxy-1-methyl-butoxy)-1-methyl-pent-4-enyl]-carbamic acid benzyl ester 
• 113283-79-7 [(1S,2R)-2-((1S,3S)-3-Hydroxy-1-methyl-butoxy)-1-methyl-pent-4-enyl]-carbamic acid benzyl ester 
• 55707-41-0 2-amino-3,3-dimethoxypropane 

Relevant academic research and scientific papers

Protecting-group-free total synthesis of (-)-rhazinilam and (-)-rhazinicine using a gold-catalyzed cascade cyclization

'Rhaz'zmatazz: A total synthesis of (-)-rhazinilam and the first asymmetric total synthesis of (-)-rhazinicine were accomplished by using constructing the indolizinone core through the gold-catalyzed cyclization of a fully elaborated linear ynamide. The scope and generality of this cascade reaction for the construction of highly substituted indolizinones were also investigated. Copyright

Asymmetric Synthesis of 2- Amino Alcohol Derivatives from (S)-α-Amino Aldehydes via Acetal Templates

Titanium tetrachloride mediated addition of allyltrimethylsilane to chiral acetals derived from (S)-α-amino aldehydes and (+)-(2S,4S)-pentane-2,4-diol gave the anti-2-amino alcohol derivatives with considerably high diastereoselectivity.On the other hand,

DIASTEREOSELECTIVE SYNTHESIS OF 2,3-CIS-2-ALKYL-3-OXYGENATED PIPERIDINE DERIVATIVES BY TITANIUM MEDIATED INTRAMOLECULAR CYCLIZATION OF α-AMINOACETAL-ALLYLSILANE SYSTEM

(2S,3S)-2-Alkyl-3-oxygenated 5-methylenepiperidines were obtained with high diastereoselectivity by cyclization of N-methoxycarbonyl-N-silylmethallyl-α-alkylaminoacetaldehyde ethyleneacetals with TiCl3(OPri).

Compounds for treating hypertension

Compounds of the formula STR1 and their pharmaceutically acceptable salts, wherein the substituents are as defined herein, having antihypertensive activity.