299207-22-0Relevant academic research and scientific papers
γ-Carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity
Sako, Kumiko,Aoyama, Hiroshi,Sato, Shinichi,Hashimoto, Yuichi,Baba, Masanori
, p. 3780 - 3790 (2008/12/20)
Based on anti-viral screening of our heteroaromatics derived from thalidomide, the γ-carboline skeleton has been identified as a superior scaffold structure for compounds with potent anti-bovine viral diarrhea virus (BVDV) activity. Structural development studies led to a potent anti-viral agent, SK5M (5-methyl-γ-carboline), with the EC50 of 0.26 μM.
Solid-phase synthesis of C-terminal peptide aldehydes from amino acetals anchored to a backbone amide linker (BAL) handle
Guillaumie,Kappel,Kelly,Barany,Jensen
, p. 6131 - 6135 (2007/10/03)
Peptide aldehydes were synthesized, starting from amino acetals, by a Solid-phase backbone amide linker (BAL) strategy. (C) 2000 Elsevier Science Ltd.
DIASTEREOSELECTIVE SYNTHESIS OF 2,3-CIS-2-ALKYL-3-OXYGENATED PIPERIDINE DERIVATIVES BY TITANIUM MEDIATED INTRAMOLECULAR CYCLIZATION OF α-AMINOACETAL-ALLYLSILANE SYSTEM
Kano, Shinzo,Yokomatsu, Tsutomu,Iwasawa, Haruo,Shibuya, Shiroshi
, p. 2805 - 2809 (2007/10/02)
(2S,3S)-2-Alkyl-3-oxygenated 5-methylenepiperidines were obtained with high diastereoselectivity by cyclization of N-methoxycarbonyl-N-silylmethallyl-α-alkylaminoacetaldehyde ethyleneacetals with TiCl3(OPri).
