112084-93-2

Upstream product

• 24517-64-4 2-amino-3-pyridinecarbonitrile 
• 98-88-4 benzoyl chloride 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 112085-02-6 2-(benzoylamino)pyridine-3-carboxamide oxime 
• 112085-00-4 N-Hydroxy-N'-(3-[1,2,4]oxadiazol-3-yl-pyridin-2-yl)-benzamidine 
• 112084-97-6 3-(dimethylaminomethyleneamino)-2-phenylpyrido<2,3-d>pyrimidine-3-oxide 
• 112084-95-4 4-amino-2-phenylpyrido<2,3-d>pyrimidine-3-oxide 
• 112084-99-8 2-benzoylamino-3-(1',2',4'-oxadiazolyl-3')pyridine 

Downstream Products

• 112084-94-3 4-hydroxylamino-2-phenylpyrido<2,3-d>pyrimidine 
• 112085-02-6 2-(benzoylamino)pyridine-3-carboxamide oxime 
• 41803-67-2 4-chloro-2-phenylpyrido[2,3-d]pyrimidine 
• 41803-68-3 4-Amino-2-phenylpyrido<2,3-d>pyrimidin 
• 16081-87-1 2-phenylpyrido<2,3-d>pyrimidin-4(3H)-one 
• 112084-97-6 3-(dimethylaminomethyleneamino)-2-phenylpyrido<2,3-d>pyrimidine-3-oxide 
• 112084-99-8 2-benzoylamino-3-(1',2',4'-oxadiazolyl-3')pyridine 
• 112085-01-5 2-aminopyridine-3carboxamide-O-benzoyloxime 
• 112084-98-7 3-Hydroxy-2-phenyl-3H-pyrido[2,3-d]pyrimidin-4-one 
• 112084-95-4 4-amino-2-phenylpyrido<2,3-d>pyrimidine-3-oxide 
• 112084-96-5 2-benzoylaminonicotinamide 
• 82216-41-9 2-amino-3-(5'-phenyl-1',2',4'-oxadiazolyl-3')pyridine 

Relevant academic research and scientific papers

Pd-Catalyzed tandem reaction of N-(2-cyanoaryl)benzamides with arylboronic acids: synthesis of quinazolines

The synthesis of 2,4-disubstituted quinazolines by a palladium-catalyzed reaction of arylboronic acids with N-(2-cyanoaryl)benzamides has been developed with moderate to excellent yields. The method shows good functional group tolerance. In particular, ha

Convenient and practical one-pot synthesis of 4-chloropyrimidines via a novel chloroimidate annulation

Reaction of aromatic or heteroaromatic 2-acyl(amino)nitriles with phosphorus pentachloride triggers a novel chloroimidate cyclization, leading directly to the corresponding annullated 4-chloropyrimidines in good to excellent yields. The reaction lends itself to the telescoped one-pot construction of 4-functionalized pyrimidines from the corresponding (hetero)aromatic 2-aminonitriles. For a pyrazolopyrimidine development intermediate, this reaction was scaled up to multikilogram scale with excellent results. A total of 10 examples with different substrates are provided. This one-pot reaction provides an attractive and sustainable alternative to the commonly used multistep methodology for this transformation.

Synthesis and Transformations of Some Pyridopyrimidines

A new synthetic approach for pyridopyrimidine 3-oxides and other pyridopyrimidines has been developed.This bicyclic system readily undergoes ring opening to give a variety of products, depending on the reagent and reaction conditions. - Keywords: Cyclization with C-N or C-O bond formation; Ring opening; Substituted pyridines; Substituted 1,2,4-oxadiazoles