1121-39-7

Basic information

• Product Name: Bicyclo[4.1.0]heptane, 7-bromo-
• CAS NO: 1121-39-7
• Molecular Formula: C7H11Br
• Molecular Weight: 175.068
• Mol File: 1121-39-7.mol

Chemical Properties

• CAS DataBase Reference: Bicyclo[4.1.0]heptane, 7-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: Bicyclo[4.1.0]heptane, 7-bromo-(1121-39-7)
• EPA Substance Registry System: Bicyclo[4.1.0]heptane, 7-bromo-(1121-39-7)

Safety Data

• Hazardous Substances Data: 1121-39-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Bicyclo[4.1.0]heptane, 7-bromois used as a building block for the synthesis of various pharmaceuticals due to its unique chemical reactivity and versatility. It serves as a key intermediate in the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, Bicyclo[4.1.0]heptane, 7-bromois utilized as a starting material for the synthesis of various agrochemicals, such as pesticides and herbicides, owing to its chemical properties and reactivity.
Used in Research and Development:
Bicyclo[4.1.0]heptane, 7-bromois also employed in research and development as a starting material for the preparation of various organic compounds. It aids scientists in exploring new chemical reactions and synthesizing novel organic molecules for potential applications in various fields.

Upstream product

• 109-99-9 tetrahydrofuran 
• 3591-63-7 7-exo-bromo-7-endo-chlorobicyclo<4.1.0>heptane 
• 2415-79-4 7,7-dibromonorcarane 
• 86901-19-1 9,10-dihydro-9,10-anthracendiyl-tris(THF)magnesium 
• 676-58-4 methylmagnesium chloride 
• 920-39-8 isopropylmagnesium bromide 

Downstream Products

• 90245-79-7 C₁₉H₂₁P 
• 89657-20-5 trans-7-(phenylthio)bicyclo[4.1.0]heptane 
• 91842-51-2 (1S,6R,7S)-7-Butylsulfanyl-bicyclo[4.1.0]heptane 
• 90245-80-0 Bicyclo[4.1.0]hept-7-yl-diphenyl-arsane 
• 87944-11-4 (7-Norcaranyl)diphenylphosphin oxide 

Relevant articles and documents

Some reactions of gem-dibromocyclopropanes and metal carbonyls

A series of gem-dibromocyclopropanes were treated with various metal complexes. Among the metal complexes, Ru(CO)2(PPh3) 3, Ru(CO)3(PPh3)2, and Mo(CO) 6 were able to remove a bro

Bromine-magnesium exchange in gem-dibromocyclopropanes using Grignard reagents

Reaction of gem-dibromocyclopropanes with ethylmagnesium bromide at ambient temperature leads to very high yields of allenes; when cyclopropylidene-allene ring opening is suppressed, alternative carbenic products are observed, although other reactions compete. When the reactions are carried out at -60°C, a 1-bromo-1-(bromomagnesio)-cyclopropane is formed which may be trapped by a number of electrophiles.

Dehalogenation of Geminal Dihalocyclopropanes, α,α-Dichlorocyclobutanones, and Haloketones by Means of Magnesium Anthracene*3THF

1,1-Dichloro-2,2,3,3-tetramethylcyclopropane (1a), 7,7-dichloro- and 7,7-dibromonorcarane (1b) react with magnesium anthracene*3THF (2) under stepwise radical reduction to give 9a,b, 11a,b and 10, carbene products 6a,a',b and 7a,b, and the alkylation products 4a,b and 5a,b, respectively.The distribution of the reaction products is strongly dependent upon the substrate and upon the reaction conditions: for instance, 1a in toluene undergoes a highly selective reduction to yield 9a, whereas in THF at low temperature 4a and 5a predominate.The reaction course proposed for the reaction of 1a with 2 is supported by deuteration experiments. α,α-Dichlorocyclobutanones 12a-e can be reduced with 2 to give α-chlorocyclobutanones 13a-e in moderate to good yields; 12d is thereby converted in high purity into endo-13d.The reduction of 2-haloketones 15a-f with 2 in THF to the ketones 16a-f is possible only in low or moderate yields.

Low-temperature Reaction of gem-Dihalocyclopropanes with Activated Magnesium

The reaction of 7-bromo-7-chlorobicycloheptane and 7-bromo-7-fluorobicycloheptane with activated magnesium in THF at -50 to -40 deg C gave 7-bromobicycloheptane, in addition to 7-chloro- and 7-fluorobicycloheptane, respectively.