112142-72-0Relevant academic research and scientific papers
Selective Amide Cleavage in Peptides Containing α,α-Disubstituted α-Amino Acids
Wipf, Peter,Heimgartner, Heinz
, p. 354 - 368 (1987)
A new synthesis of dipeptides with terminal α,α-disubstituted α-amino acids, using 2,2-disubstituted 3-amino-2H-azirines 1 as amino-acid equivalents, is demonstrated.The reaction of 1 with N-protected amino acids leads to the corresponding dipeptide amide
