112168-16-8

Upstream product

• 124-41-4 sodium methylate 
• 112168-15-7 (R)-3-[2-((1R,6S)-6-Phenylsulfanylcarbonylmethyl-cyclohex-3-enyl)-acetyl]-2-thioxo-thiazolidine-4-carboxylic acid methyl ester 
• 108-98-5 thiophenol 
• 112168-18-0 (1R-cis)-4-cyclohexene-1,2-diacetic acid monomethyl ester 
• 120926-19-4 (S)-3-[2-((1S,6R)-6-Phenylsulfanylcarbonylmethyl-cyclohex-3-enyl)-acetyl]-2-thioxo-thiazolidine-4-carboxylic acid methyl ester 
• 112168-17-9 ((1S,6R)-6-Phenylsulfanylcarbonylmethyl-cyclohex-3-enyl)-acetic acid 

Downstream Products

• 112168-22-6 [3aS-(3aα,4α,5β,6aα)]-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]hexahydro-5-[(tetrahydro-2H-pyran-2-yl)oxy]-2(1H)-pentalenone 
• 113435-68-0 (1S,3aR,7aR)-2-Oxo-2,3,3a,4,7,7a-hexahydro-1H-indene-1-carbothioic acid S-phenyl ester 

Relevant academic research and scientific papers

A new enantiodivergent procedure utilising the chemoselective Dieckmann-type cyclisation of chiral mono-thiol diesters

The chiral mono-thiol diester, 1 or 2, is converted to the corresponding enantiomeric cyclised products, (-)-7 and (+)-7 or (-)-9 and (+)-9, depending on whether LDA or A1Cl3-Et3N is used.