1122-39-0

Usage

Uses

Used in Pharmaceutical Industry:
2,4,5-trimethylpyridine is used as a solvent and intermediate for the synthesis of various pharmaceutical compounds, leveraging its ability to dissolve a wide range of substances and facilitate chemical reactions.
Used in Dye Industry:
In the dye industry, 2,4,5-trimethylpyridine is utilized as a solvent and intermediate, contributing to the production of dyes by aiding in the dissolution and reaction processes required for dye synthesis.
Used in Pesticide Industry:
2,4,5-trimethylpyridine is employed as a solvent and intermediate in the formulation of pesticides, enhancing the effectiveness of these agricultural chemicals by improving their solubility and stability.
Used as a Corrosion Inhibitor:
2,4,5-trimethylpyridine is used as a corrosion inhibitor in various applications, protecting metal surfaces from degradation and extending the lifespan of equipment and structures.
Used in Organic Synthesis:
As a starting material in the synthesis of other organic compounds, 2,4,5-trimethylpyridine plays a crucial role in the creation of a diverse range of chemical products, from specialty chemicals to advanced materials.

InChI:InChI=1/C8H11N/c1-6-4-8(3)9-5-7(6)2/h4-5H,1-3H3

Upstream product

• 100859-71-0 3,4,6-trimethyl-1,2-dihydro-pyridine 
• 856851-22-4 5-chloromethyl-2,4-dimethyl-pyridine 
• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 75-05-8 acetonitrile 
• 50-00-0 formaldehyd 
• 67-64-1 acetone 
• 63644-88-2 (4,6-Dimethyl-[3]pyridyl)-methanol 

Downstream Products

• 859189-82-5 4-methyl-pyridine-2,5-dicarboxylic acid 
• 490-28-8 pyridine-2,4,5-tricarboxylic acid 

Relevant academic research and scientific papers

Inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction

The invention concerns inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction, characterized by formula I wherein, X, Y and Z independently represent C or N; ------ is an optional double bond; n is 0 or 1; R1, R2, and R4 independently represent hydrogen, a chemical bond, C1-10 alkyl; C2-10 alkenyl; C2-10 alkinyl; aryl; aryl-C1-10 alkyl; C3-10 heterocyclyl; C5-10 heteroaryl; halo, CF3; NO2; NHC(O)R*, OR, said alkyl, alkenyl, alkinyl, aryl, arylalkyl, heterocyclyl, or heteroaryl being optionally substituted; R3, R5, and R6 independently represent hydrogen, C1-10alkyl; C2-10 alkenyl; C2-10 alkinyl; aryl; aryl-C1-10alkyl; C3-10 heterocyclyl; C5-10 heteroaryl; halo, CF3; NO2; NHC(O)R*, OR, said alkyl, alkenyl, alkinyl, aryl, heterocyclyl, or heteroaryl being optionally substituted; or R5 and R6 together form a 5- or 6-member aryl, heterocyclyl or heteroaryl group; R is hydrogen or C1-6 alkyl; R* is hydrogen, or C1-6 alkyl, or OH, wherein the optional substituents are preferably selected from the group of one to three OH, C1-6 alkyl, halo, NO2, C1-6 alkoxy, and CF3, or a pharmaceutically acceptable salt thereof.

An Improved Liquid-Phase Synthesis of Simle Alkylpyridines

The synthesis of pyridines from mixtures of aldehydes or ketones and NH3 in the liquid phase has been reinvestigated, using continuous dosage of the carbonyl components to the reaction mixture.The main product from the reaction of acetaldehyde and formaldehyde is 3-methylpyridine (6), which is also the main product from the reaction of acrolein or a mixture of crotonaldehyde and formaldehyde under the same conditions.The reaction of other aldehydes with formaldehyde give 3,5-dialkylpyridines, e.g. 10, 16.Acetone reacts with either formaldehyde or acetaldehyde to give polysubstituted alkylpyridines.A mechanistic pathway is proposed which accounts for the formation of the observed products.