112246-51-2

Upstream product

• 23363-33-9 4'-demethyl-4'-O-(benzoyloxycarbonyl)epipodophyllotoxin 
• 112146-51-7 C₄₁H₄₁Cl₂NO₁₆ 
• 92206-82-1 Chloro-acetic acid 4-((5S,5aS,9R)-9-hydroxy-6-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)-2,6-dimethoxy-phenyl ester 
• 477-47-4 (+/-)-podophyllotoxin 
• 6559-91-7 (+/-)-4'-O-demethyl-1-epipodophyllotoxin 
• 131118-85-9 {(2S,4aS,6S,7S,8S,8aR)-8-Hydroxy-6-[(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxy-phenyl)-8-oxo-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yloxy]-2-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl}-carbamic acid benzyl ester 
• 99194-78-2 1-O-(3,4,6-tri-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 99194-79-3 1-O-(2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 111275-65-1 2,4,6-tri-O-acetyl-3-benzyloxycarbonylamino-3-deoxy-β-D-glucopyranose 
• 2783-43-9 Acetic acid (2R,3S,4S,5R,6R)-5-acetoxy-2-acetoxymethyl-4-benzyloxycarbonylamino-6-bromo-tetrahydro-pyran-3-yl ester 
• 99194-76-0 3,4,6-tri-O-acetyl-2-{[(benzyloxy)carbonyl]amino}-2-deoxy-β-D-glucopyranose 
• 73446-41-0 3,4,6-tri-O-acetyl-2-(benzoyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl bromide 
• 111275-60-6 1-O-(2-benzyloxycarbonylamino-2-deoxy-4:6-O-ethylidene-α-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 99194-78-2 1-O-(3,4,6-tri-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 

Downstream Products

• 105655-99-0 1-O-(2-deoxy-2-dimethylamino-β-L-glucopyranosyl)-<(-)-1-epipodophyllotoxin> 
• 111275-51-5 1-O-(2-chloroethylamino-2-deoxy-4:6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-1-epipodophyllotoxin 
• 105655-99-0 1-O-(2-dimethylamino-2-deoxy-4:6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-1-epipodophyllotoxin 
• 105655-99-0 4'-O-demethyl-4-O-(2-deoxy-2-dimethylamino-4,6-O-ethylidene-α-D-glucopyranosyl)-4-epipodophyllotoxin 

Relevant academic research and scientific papers

Etoposide: a new approach to the synthesis of 4-O-(2-amino-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin

Synthesis of 3-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-4,6-O-ethylidene-α-(7α) and -β-D-glucopyranose (7β) and their 3-O-chloroacetyl analogues (11α and 11β) are described.Condensation (BF3-etherate, ethyl acetate, -20 deg C) of 7α with 4'-O-benzyloxyca

Syntheses of All Four Possible Diastereomers of Etoposide and Its Aminoglycosidic Analogues via Optical Resolution of (+/-)-Podophyllotoxin by Glycosidation with D- and L-Sugars

Syntheses of all four possible diastereomers of etoposide and its aminoglycosidic analogues have been achieved via optical resolution of (+/-)-podophyllotoxin by glycosidation with D- and L-sugars.