112253-23-3Relevant academic research and scientific papers
A Novel Two-Step Synthesis of Hexahydropyrazinoquinolines
Nijhuis, Walter H. N.,Verboom, Willem,Reinhoudt, David N.
, p. 641 - 645 (1987)
The hexahydropyrazinoquinolines 2 were prepared in good yields by reaction of 2-(4-substituted 1-piperazinyl)benzaldehydes 5 with malononitrile and subsequent thermal cyclization of the condensation products 6; the latter reaction takes place via a
