Synthesis p. 641 - 645 (1987)
Update date:2022-08-04
Topics:
Nijhuis, Walter H. N.
Verboom, Willem
Reinhoudt, David N.
The hexahydropyrazino<1,2-a>quinolines 2 were prepared in good yields by reaction of 2-(4-substituted 1-piperazinyl)benzaldehydes 5 with malononitrile and subsequent thermal cyclization of the condensation products 6; the latter reaction takes place via a
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