1122549-47-6 Usage
Description
3-(ChloroMethyl)-N-(5-chloro-2-pyridinyl)-2-pyrazinecarboxaMide is an organic compound characterized by its brown solid appearance. It is a derivative of pyrazinecarboxamide, featuring a chloromethyl group and a 5-chloro-2-pyridinyl moiety, which contribute to its chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
3-(ChloroMethyl)-N-(5-chloro-2-pyridinyl)-2-pyrazinecarboxaMide is used as an intermediate compound in the synthesis of Eszopiclone (E889150), a medication primarily prescribed for the treatment of insomnia. Its role in the preparation process is crucial for the development of the final drug product, ensuring its efficacy and quality.
Additionally, given its structural features and chemical properties, 3-(ChloroMethyl)-N-(5-chloro-2-pyridinyl)-2-pyrazinecarboxaMide may have potential applications in other areas of the pharmaceutical industry, such as the development of new drugs or the improvement of existing ones. However, further research and development would be necessary to explore these possibilities.
Check Digit Verification of cas no
The CAS Registry Mumber 1122549-47-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,2,5,4 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1122549-47:
(9*1)+(8*1)+(7*2)+(6*2)+(5*5)+(4*4)+(3*9)+(2*4)+(1*7)=126
126 % 10 = 6
So 1122549-47-6 is a valid CAS Registry Number.
1122549-47-6Relevant articles and documents
Synthesis of RP 48497, an impurity of eszopiclone
Sha, Yu,Zhang, Lei,Du, Gui-Jie,Ren, Jian,Cheng, Mao-Sheng
, p. 1817 - 1821 (2008)
RP 48497 is a photodegradation product of eszopiclone, a non-benzodiazepine sedative-hypnotic used in the treatment of insomnia. We report herein the first synthesis of RP 48497 via reduction, chlorination, and recyclization of 6-(5-chloropyridin-2-yl)-7-hydroxy-6,7-dihydropyrrolo[3,4-b]pyrazin-5-one (3), a key intermediate in the synthesis of eszopiclone. The structure of RP 48497 was confirmed by its 1H-NMR and MS data. The mechanism of the reduction step in the synthesis of RP 48497 was also studied and the key parameters were determined. These findings should be important for quality control purposes in the manufacture of eszopiclone.
