112257-05-3Relevant academic research and scientific papers
Analogues of oxytocin with an oxime bridge using chemoselectively addressable building blocks
Wahl, Franck,Mutter, Manfred
, p. 6861 - 6864 (1996)
The synthesis of two novel amino-acid building blocks for the chemoselective ligation of unprotected peptides via oxime bond formation and their application in the solid phase peptide synthesis of oxytocin analogues with the disulfide altered to an oxime bridge are described.
Construction of highly reactive probes for abasic site detection by introduction of an aromatic and a guanidine residue into an aminooxy group
Kojima, Naoshi,Takebayashi, Toshie,Mikami, Akiko,Ohtsuka, Eiko,Komatsu, Yasuo
supporting information; experimental part, p. 13208 - 13209 (2010/01/30)
(Chemical Equation Presented) Abasic sites (AP sites) arise from hydrolysis of glycosidic bonds of DNA that is damaged by various external and internal processes; unrepaired AP sites give rise to genetic mutations. We have constructed highly reactive AP-s
