Tetrahedron Letters p. 6861 - 6864 (1996)
Update date:2022-08-03
Topics: Synthesis Optimization Protecting groups Deprotection Purification and characterization Biological Evaluation Design Chemoselective Functionalization
Wahl, Franck
Mutter, Manfred
The synthesis of two novel amino-acid building blocks for the chemoselective ligation of unprotected peptides via oxime bond formation and their application in the solid phase peptide synthesis of oxytocin analogues with the disulfide altered to an oxime bridge are described.
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