112298-29-0Relevant academic research and scientific papers
New catalytic oxidation of trifluoromethyl carbinols by a ruthenium(II) complex
Kesavan, Venkitasamy,Bonnet-Delpon, Danièle,Bégué, Jean-Pierre,Srikanth, Abirami,Chandrasekaran, Srinivasan
, p. 3327 - 3330 (2000)
The first catalytic oxidation of trifluoromethyl carbinols has been accomplished by a novel ruthenium(II) complex using sodium periodate as an oxidant. Trifluoromethyl ketones were obtained under mild conditions and in excellent yields. (C) 2000 Elsevier Science Ltd.
Regioselective intramolecular oxidation of phenols and anisoles by dioxiranes generated in situ
Yang, Dan,Wong, Man-Kin,Yan, Zheng
, p. 4179 - 4184 (2007/10/03)
A novel method for regioselective oxidation of phenols and anisoles has been developed in which dioxiranes, generated in situ from ketones and Ozone, oxidize phenol derivatives in an intramolecular fashion. A series of ketones with electron-withdrawing groups, such as CF3, COOMe, and CH2Cl, were attached to phenols, anisoles, or aryl rings via a C2 or C3 methylene linker. In a homogeneous solvent system of CH3CN and H2O, oxidation of phenol derivatives 1-10 afforded spiro 2-hydroxydienones in 24-55% yields regardless of the presence of other substituents (ortho Me, meta Me or Br) on the aryl ring and the length of the linker. Experimental evidences were provided to support the mechanism that involves a regioselective π bond epoxidation of aryl rings followed by epoxide rearrangement and hemiketal formation.
The Wittig Reaction of Perfluoro Acid Derivatives: Access to Fluorinated Enol Ethers, Enamines, and Ketones
Begue, Jean-Pierre,Bonnet-Delpon, Daniele,Mesureur, Dany,Nee, Gerard,Wu, Sheng-Wen
, p. 3807 - 3814 (2007/10/02)
The preparation of novel perfluoroalkyl-substituted compounds in good yields is described.This preparation involves the Wittig reaction of a phosphonium ylide with perfluoroalkyl acid derivatives.The influence of the structure of the starting alkylidenetr
α-Trifluoromethyl-Destabilized Cations. A Route to 1-(Trifluoromethyl)tetralins by Trifluoroactolysis of 5-Aryl-1,1,1,-trifluoropentan-2-ols and Derivatives
Bonnet-Delpon, Daniele,Cambillau, Christian,Charpentier-Morize, Micheline,Jacquot, Roland,Mesureur, Dany,Ourevitch, Michele
, p. 754 - 759 (2007/10/02)
Trifluoroacetolysis of 5-aryl-1,1,1-trifluoropentan-2-ols 1 and their 2-aryl (2) and 2-methyl (3) analogues has been studied in search of a route to 1-(trifluoromethyl)tetralins.The results reflect the relative stabilities of the incipient carbocation int
