112302-89-3Relevant academic research and scientific papers
An umpolung-enabled copper-catalysed regioselective hydroamination approach to α-amino acids
Hirano, Koji,Miura, Masahiro,Nishino, Soshi
, p. 11525 - 11537 (2021)
A copper-catalysed regio- and stereoselective hydroamination of acrylates with hydrosilanes and hydroxylamines has been developed to afford the corresponding α-amino acids in good yields. The key to regioselectivity control is the use of hydroxylamine as
Synthesis of aromatic α-aminoesters: Palladium-catalyzed long-range arylation of primary Csp3-H bonds
Aspin, Sam,Goutierre, Anne-Sophie,Larini, Paolo,Jazzar, Rodolphe,Baudoin, Olivier
supporting information, p. 10808 - 10811 (2013/01/15)
Remote control: The title reaction for β-Iζ arylation of α-amino esters with aryl bromides is described. This reaction, which occurs selectively at the terminal position of linear alkyl chains, gives rise to synthetically useful (hetero)arylalanines and homologues after debenzylation (see scheme). Copyright
Copper-catalyzed amination of ketene silyl acetals with hydroxylamines: Electrophilic amination approach to α-amino acids
Matsuda, Naoki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
, p. 11827 - 11831 (2013/01/15)
Role reversal: The title reaction has been developed to deliver α-amino acids under very mild reaction conditions (see scheme; dpppen=1,5-bis(diphenylphosphino)pentane). The catalysis provides a new C-N bond-forming approach for the synthesis of α-amino a
Alkylation and Condensation Reactions of N,N-Dibenzylglycine Esters: Synthesis of α-Amino Acid Derivatives
Gray, Brian D.,Jeffs, Peter W.
, p. 1329 - 1330 (2007/10/02)
Upon deprotonation N,N-dibenzylglycine esters undergo alkylation and condensation reactions at the α-carbon atom with various electrophiles.
