112393-76-7Relevant articles and documents
REACTION OF METHOXY-N-HETEROAROMATICS WITH PHENYLACETONITRILE UNDER BASIC CONDITIONS
Yamanaka, Hiroshi,Ohba, Setsuya
, p. 895 - 909 (2007/10/02)
The monomethoxyl derivatives of various ?-electron deficient N-heteroaromatics reacted with phenylacetonitrile in tetrahydrofuran in the presence of sodium hydride to give α-phenyl-N-heteroareneacetonitriles in the yields ranging from 45 to 78percent.On the contrary, the reaction of these methoxyl derivatives with ethyl cyanoacetate or malononitrile under similar conditions was restricted within narrow limits.The synthesis of benzoyl-N-heteroaromatics by the air-oxidation of α-phenyl-N-hetroareneacetonitriles was described additionally.
STUDIES ON AS-TRIAZINE DERIVATIVES. IX. SYNTHESIS OF 5-SUBSTITUTED 1,2,4-TRIAZINE DERIVATIVES THROUGH AN ADDITION REACTION AND SUBSEQUENT OXIDATION
Konno, Shoetsu,Ohba, Setsuya,Sagi, Mataichi,Yamanaka, Hiroshi
, p. 1378 - 1382 (2007/10/02)
The addition reactions of various nucleophiles to 6-methyl-3-phenyl-1,2,4-triazine (1) were investigated and a practical preparation of 1 was developed.The reactions showed many similarities to those of quinazoline (at the 4-position) and acridine (at the