33449-34-2

Upstream product

• 114165-38-7 N'-(1-cyano-ethylidene)-benzohydrazonoyl chloride 
• 27318-25-8 3⁽⁵⁾-methyl-5⁽³⁾-phenyl-4-nitrosopyrazole 
• 960-16-7 tributylphenylstannane 
• 615-76-9 6-aza-2-thiothymine 
• 28819-30-9 benzamidrazone 
• 127-17-3 2-oxo-propionic acid 

Downstream Products

• 94398-25-1 5-chloro-6-methyl-3-phenyl-2,5-dihydro-as-triazine 
• 112393-76-7 ethyl-α-cyano-6-methyl-3-phenyl-as-triazine-5-acetate 
• 112393-73-4 5-hydrazino-6-methyl-3-phenyl-as-triazine 
• 107126-32-9 6-methyl-3-phenyl-as-triazine-5-carbonitrile 
• 94398-40-0 6-methyl-3-phenyl-5-as-triazinylmethyl phenyl ketone 
• 116177-94-7 5-Ethoxy-6-methyl-3-phenyl-[1,2,4]triazine 
• 54673-31-3 5-methoxy-6-methyl-3-phenyl-[1,2,4]triazine 
• 107126-33-0 5,5'-bis(6-methyl-3-phenyl-as-triazinyl) 
• 107126-31-8 6-methyl-3-phenyl-2,5-dihydro-as-triazine-5-sulfonic acid monohydrate 
• 112393-72-3 6-methyl-3-phenyl-as-triazine-5-carboxamide 
• 112393-74-5 5,6-dimethyl-3-phenyl-2,5-dihydro-as-triazine 
• 112393-75-6 6-methyl-3-phenyl-2,5-dihydro-as-triazine 
• 37967-82-1 6-methyl-3-phenyl-1,2,4-triazine 
• 112393-77-8 α-phenyl-6-methyl-3-phenyl-as-triazine-5-acetonitrile 

Relevant academic research and scientific papers

Desulfitative cross-coupling of protecting group-free 2-thiouracil derivatives with organostannanes

We here report a unique and efficient copper bromide mediated pallado-catalyzed coupling of protecting group-free 2-thiouracil derivatives with organostannanes. The nature of the copper appears to be crucial for successful cross coupling.

Angiotensin II receptor antagonistic 1,2,4-triazin-5-one derivatives

Disclosed are novel 1,2,4-triazin-5-one biphenyl derivatives having structural formula (I) useful as non-peptide antagonists of angiotensin II receptor: where R1 represents alkyl, cycloalkyl, or substituted or unsubstituted aryl; R2 represents alkyl, substituted or unsubstituted aryl, or arylalkyl; A and D independently represent C-R3, N, NH or C=O, wherein when A and D independently denote C-R3 or N, b and c are independently a double bond, and when A and D independently denote NH or C=O, b and c are independently a single bond; provided that b and c are not both double bonds; and R3 is hydrogen, dialkylphosphonate or halogen; and pharmaceutically acceptable salts thereof. Also disclosed is the use of the compounds of formula (I) as non-peptide antagonists of angiotensin II receptor, in the treatment of cardiovascular diseases, in particular hypertension and congestive heart failure.

1,2,4-Triazines. II. New Zwitterionic Methylation Products of Some 1,2,4-Triazin-5(2H)-ones and Their Identification by Carbon-13 Nuclear Magnetic Resonance Spectroscoy

The methylation of various 3- and 6-substituted 1,2,4-triazin-5(2H)-one derivatives yield new zwitterionic N 1 methylation products in addition to the previously reported 2-, 4- and O-methyl isomers.Specifically, 3-phenyl-1,2,4-triazin-5(2H)-one and its 6

STUDIES ON as-TRIAZINE DERIVATIVES. IV. SYNTHESIS OF UNSYMMETRICAL 5,6-DISUBSTITUTED 1,2,4-TRIAZINES

The reaction of 5-chloro-6-methyl-3-phenyl-1,2,4-triazine (4a) with ethylidenetriphenylphosphorane followed by the hydrolysis of the resulting as-triazinylphosphorane afforded 5-ethyl-6-methyl-3-phenyl-1,2,4-triazine (6a) in 88 percent yield.The condensat