37967-82-1

Upstream product

• 94398-25-1 5-chloro-6-methyl-3-phenyl-2,5-dihydro-as-triazine 
• 107126-31-8 6-methyl-3-phenyl-2,5-dihydro-as-triazine-5-sulfonic acid monohydrate 
• 1464-98-8 N-(prop-2-yn-1-yl)benzamide 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 33449-34-2 6-methyl-5-oxo-3-phenyl-2,5-dihydro-as-triazine 
• 112393-75-6 6-methyl-3-phenyl-2,5-dihydro-as-triazine 

Downstream Products

• 107126-32-9 6-methyl-3-phenyl-as-triazine-5-carbonitrile 
• 112393-73-4 5-hydrazino-6-methyl-3-phenyl-as-triazine 
• 112393-72-3 6-methyl-3-phenyl-as-triazine-5-carboxamide 
• 107126-33-0 5,5'-bis(6-methyl-3-phenyl-as-triazinyl) 
• 107126-31-8 6-methyl-3-phenyl-2,5-dihydro-as-triazine-5-sulfonic acid monohydrate 
• 94398-40-0 6-methyl-3-phenyl-5-as-triazinylmethyl phenyl ketone 
• 112393-76-7 ethyl-α-cyano-6-methyl-3-phenyl-as-triazine-5-acetate 
• 112393-77-8 α-phenyl-6-methyl-3-phenyl-as-triazine-5-acetonitrile 
• 24108-42-7 5,6-dimethyl-3-phenyl-1,2,4-triazine 

Relevant academic research and scientific papers

Modular synthesis of 3,6-disubstituted-1,2,4-triazines via the cyclodehydration of β-keto- N -acylsulfonamides with hydrazine salts

A straightforward method for preparing 3,6-disubstituted-1,2,4-triazines through a redox-efficient cyclodehydration of β-keto-N-acylsulfonamides with hydrazine salts is described. Two approaches for synthesizing the requisite β-keto-N-acylsulfonamides are presented, which allow for the late stage incorporation of either the C3 or C6 substituent in a flexible manner from acid chlorides or α-bromoketones, respectively. The scope of this methodology includes primary and secondary sp3-linked substituents at both the C3 and C6 positions, and the mild reaction conditions tolerate a variety of sensitive functionalities.

Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH2: A novel entry into the 1,2,4-triazine core

Hydrohydrazination of a variety of propargylamides with BocNHNH2 under Zn(OTf)2 catalysis, unexpectedly, gave dihydro-1,2,4-triazines with a loss of the protecting group. The initial products can be efficiently aromatized in situ wit

STUDIES ON AS-TRIAZINE DERIVATIVES. IX. SYNTHESIS OF 5-SUBSTITUTED 1,2,4-TRIAZINE DERIVATIVES THROUGH AN ADDITION REACTION AND SUBSEQUENT OXIDATION

The addition reactions of various nucleophiles to 6-methyl-3-phenyl-1,2,4-triazine (1) were investigated and a practical preparation of 1 was developed.The reactions showed many similarities to those of quinazoline (at the 4-position) and acridine (at the

STUDIES ON as-TRIAZINE DERIVATIVES. VII. RESEMBLANCE BETWEEN as-TRIAZINES AND QUINAZOLINES IN NUCLEOPHILIC ADDITION-ELIMINATION REACTIONS.

Alike 4-chloroquinazoline, 5-chloro-1,2,4-triazines (as-triazines) reacted with aromatic aldehydes in the presence of 1,3-dimethylbenzimidazolium iodide under basic conditions to give 5-aroyl-as-triazines.The Grignard reaction of 5-cyano-as-triazine with arylmagnesium bromides failed to give any significant product.Some analogy of as-triazines with quinazolines, in their chemical properties, was additionally investigated.