1124-98-7

Usage

Structure

Contains a cyclohexane ring and an ethyl group

Type of compound

Carboxylic acid derivative

Applications

a. Intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals
b. Building block for creating a wide range of organic compounds
c. Used in the production of flavor and fragrance chemicals
d. Potential applications in the development of materials in the pharmaceutical and pharmaceutical industries

Upstream product

• 1940-18-7 1-ethylcyclohexanol 
• 55443-01-1 ethyl 2-oxo-1-ethyl-1-cyclohexanecarboxylate 
• 14064-13-2 (1-methylcyclohexyl)methanol 
• 2891-49-8 1-(1-ethyl-cyclohexyl)-propan-1-one 
• 201230-82-2 carbon monoxide 
• 1453-24-3 1-ethylcyclohexene 
• 64-18-6 formic acid 
• 931-88-4 cis-Cyclooctene 
• 7664-93-9 sulfuric acid 
• 3761-94-2 1-methylcycloheptanol 
• 1123-25-7 1-methyl-1-cyclohexanecarboxylic acid 
• 7443-52-9 (+/-)-trans-2-methylcyclohexanol 
• 5454-79-5 cis-3-methylcyclohexanol 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 

Downstream Products

• 41417-86-1 (1-ethylcyclohexyl)methanol 
• 1029128-58-2 ethylcyclohexylcarbonyl chloride 
• 56164-66-0 1-propyl-cyclohexanecarboxylic acid 
• 99175-66-3 1-propyl-cyclohexanecarboxylic acid amide 
• 2893-02-9 1-<1-Aethyl-cyclohexyl>-2-methyl-propan-1-on 
• 2891-42-1 (1-ethyl-cyclohexyl)-phenyl ketone 
• 2893-06-3 1-acetyl-1-ethylcyclohexane 
• 2891-49-8 1-(1-ethyl-cyclohexyl)-propan-1-one 
• 1309164-51-9 N-((2S,3R)-3-hydroxy-4-(N-isobutyl-4-nitrophenylsulfonamido)-1-phenylbutan-2-yl)-2-((S)-tetrahydrofuran-3-yloxy)acetamide 
• 1613614-51-9 1-ethyl-N-(quinolin-8-yl)cyclohexane-1-carboxamide 

Relevant academic research and scientific papers

Copper-catalyzed site-selective intramolecular amidation of unactivated C(sp3)-H bonds

The intramolecular dehydrogenative amidation of aliphatic amides, directed by a bidentate ligand, was developed using a copper-catalyzed sp3 C-H bond functionalization process. The reaction favors predominantly the C-H bonds of β-methyl groups over the unactivated methylene C-H bonds. Moreover, a preference for activating sp3 C-H bonds of β-methyl groups, via a five-membered ring intermediate, over the aromatic sp2 C-H bonds was also observed in the cyclometalation step. Additionally, sp3 C-H bonds of unactivated secondary sp3 C-H bonds could be functionalized by favoring the ring carbon atoms over the linear carbon atoms. Getting ahead on tams: The intramolecular dehydrogenative amidation of aliphatic amides, directed by a bidentate ligand, was developed using a copper-catalyzed sp 3 C-H bond functionalization process to deliver β-lactams. The reaction favors the C-H bonds of β-methyl groups over the unactivated methylene C-H bonds, as well as aromatic C(sp2)-H bonds and unactivated secondary C(sp3)-H bonds of rings.

NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS

The present invention relates to carboxamide derivatives of Formula (I), where B1, B2, X, L, n, R, R1, R2, Z1, Z2, Rx and Ry are as defined in the claims, as compounds and compositions for inhibiting Human Immunodeficiency Virus (HIV) and process for making the compounds.

Pharmaceutically active cyclohexyl compounds and their preparation

The chemical compounds of the invention are useful as the active compound in drugs because of their anticonvulsant and/or antianoxic activity. They have the general formula STR1 wherein Z is a hydroxyl group; a group--OM wherein M is an alkali metal atom or an equivalent atom fraction of an alkaline-earth metal or an amino group such as --NH2, and R is a linear or branched alkyl group containing from 1 to 9 carbon atoms, and optionally substituted by one or more halogen atoms; a linear or branched alkenyl or alkynyl, alkoxyalkyl, or acylalkyl group containing from 2 to 9 carbon atoms and optionally substituted by one or more halogen atoms; an aryl or arylalkyl or aryloxyalkyl group comprising at least one aromatic radical and an alkyl chain having from 1 to 4 carbon atoms.