1124382-72-4

Basic information

• Product Name: 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
• Synonyms: 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine;8-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;2-AMino-8-broMo[1,2,4]triazolo[1,5-a]pyridine;EOS-61162
• CAS NO: 1124382-72-4
• Molecular Formula: C₆H₅BrN₄
• Molecular Weight: 213.0347
• EINECS: 200-258-5
• Mol File: 1124382-72-4.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• Density: 2.09
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.83±0.30(Predicted)
• CAS DataBase Reference: 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine(1124382-72-4)
• EPA Substance Registry System: 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine(1124382-72-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1124382-72-4(Hazardous Substances Data)

Usage

General Description

8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine is a chemical compound with the molecular formula C6H5BrN4. It is a member of the triazolo-pyridine family and is characterized by its bromine substituent. 8-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine has potential uses in pharmaceutical research, particularly in the development of new drugs due to its ability to interact with biological targets. It is important to handle this chemical with care as it may have hazardous properties, and proper safety precautions should be taken when working with it in laboratory settings.

Upstream product

• 13534-99-1 2-Amino-3-bromopyridine 
• 16182-04-0 Ethoxycarbonyl isothiocyanate 
• 1124383-00-1 N-(3-bromo-2-pyridinyl)-N’-carboethoxy-thiourea 

Downstream Products

• 1319068-99-9 8-(4-chloro-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine 
• 1257704-11-2 [8-(2-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-phenylamine 
• 1257704-27-0 [8-(3-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-phenylamine 
• 1257704-14-5 [8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-phenylamine 
• 1257705-65-9 (3-methanesulfonylphenyl)-[8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amine 
• 1257705-64-8 (4-methanesulfonylphenyl)-[8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amine 
• 1257704-47-4 [8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-(3-morpholin-4-yl-phenyl)amine 
• 1257704-12-3 [8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-(4-morpholin-4-yl-phenyl)amine 
• 1257704-57-6 {[8-(4-methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]-pyridin-2-yl]-[3-(4-methyl-piperazin-1-yl)-phenyl]-amine} 
• 1257704-52-1 [8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(4-methylpiperazin-1-yl)phenyl]amine 
• 1257705-68-2 [8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-methylpiperazin-1-ylmethyl)phenyl]amine 
• 1257705-72-8 N-{3-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}-8-[4-(methylsulfonyl)phenyl][1,2,4]triazolo[1,5-a]pyridin-2-amine 
• 1257704-86-1 [8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[3-(4-morpholin-4-ylpiperidin-1-yl)phenyl]amine 
• 1257704-88-3 [8-(4-methanesulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-{3-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amine 

Relevant articles and documents

TRIAZOLO PYRIDINES AS MODULATORS OF GAMMA-SECRETASE

The present invention relates to triazolo pyridines of formula (II) and their use as modulators of ?-secretase. In particular, the present invention relates to compounds which interfere with ?-secretase and/or its substrate and therefore modulate the form

Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators

The identification and optimization of a novel series of centrally efficacious gamma secretase modulators (GSMs) offering an alternative to the privileged aryl imidazole motif is described. Chiral bicyclic tetrahydroindazolyl amine substituted triazolopyr

An Improved Synthesis of the Free Base and Diglycolate Salt of CEP-33779; A Janus Kinase 2 Inhibitor

CEP-33779 is a triazole that has been reported to show highly selective inhibition of Janus kinase 2 (JAK2). An efficient process to form CEP-33779 will be presented that uses multiple palladium couplings to provide the drug substance in a convergent mann