112497-22-0

Upstream product

• 153025-58-2 (3S,5S)-6-(benzyloxy)-1-(tert-butyldiphenylsilyloxy)-3,5-dihydroxyhexane 
• 77-76-9 2,2-dimethoxy-propane 
• 112497-21-9 (4S,6S)-6-<(benzyloxy)methyl>-4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxacyclohexane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 30379-55-6 benzyloxyacetic acid 
• 112497-12-8 (S)-1-Benzyloxy-3-[1,3]dithian-2-yl-propan-2-ol 
• 112497-11-7 (R)-1-Benzyloxy-3-p-tolylsulfanyl-propan-2-ol 
• 112497-15-1 (1S,3S)-4-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-[1,3]dithian-2-yl-butan-1-ol 
• 112497-18-4 (4R,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde 
• 112497-17-3 (4S,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxane-4-carbaldehyde 
• 112497-13-9 (3S)-4-benzyloxy-3-tert-butyldimethylsilyloxybutanal 
• 253431-95-7 ((S)-1-Benzyloxymethyl-2-[1,3]dithian-2-yl-ethoxy)-tert-butyl-dimethyl-silane 
• 112497-16-2 (4S,6S)-4-Benzyloxymethyl-6-[1,3]dithian-2-yl-2,2-dimethyl-[1,3]dioxane 
• 112497-10-6 (R)-1-Benzyloxy-3-((R)-toluene-4-sulfinyl)-propan-2-ol 

Downstream Products

• 112497-21-9 (4S,6S)-6-<(benzyloxy)methyl>-4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxacyclohexane 
• 214345-66-1 ((4S,6S)-6-(2-(tert-butyldiphenylsilyloxy)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)methanol 
• 112497-23-1 Trifluoro-methanesulfonic acid (4S,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-ylmethyl ester 
• 112497-24-2 (S)-((4R,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-(2-{(4S,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-ylmethyl}-[1,3]dithian-2-yl)-methanol 
• 151140-37-3 ((4R,6S)-6-Benzyloxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-acetic acid 
• 92757-83-0 (3R,5S)-6-Benzyloxy-3,5-dihydroxy-hexanoic acid 
• 92757-18-1 (4R,6S)-6-(benzyloxy)methyl-4-hydroxy-tetrahydro-2-pyrone 

Relevant academic research and scientific papers

A first convergent synthesis of the polyolic fragment of the antifungal pentaene macrolide strevertene A

The C(4-14) polyolic segment of antifungal macrolide strevertenes has been synthesized for the first time in protected form, incorporating four stereogenic centers. The synthetic strategy developed is based on the connection of two subunits prepared start

Diastereoface differentiation in addition of lithium enolates to chiral α, β-epoxyaldehydes

The aldolisation reaction of lithium ester enolates with chiral α,β-epoxyaldehydes 2a-2f has been investigated. The reaction proceeds with diastereofacial preference in favour of the anti isomer (anti: syn ≈ 4:1) and can be greatly enhanced in the case of

Diastereoselection in the addition of enolates to chiral α,β-epoxyaldehydes

The stereochemistry of addition of lithium enolates to the α,β-epoxyaldehydes 1z-3 has been investigated. Moderate to high diastereoselectivity (up to 13:1) is obtained in favour of the anti isomer, which is explained by the Felkin-Anh model for asymmetric induction.