112520-82-8Relevant articles and documents
Synthesis of α-Arylated Phenylsulfonylacetonitriles. A Useful Precursor for Substituted α-Arylalkanoic Acid and Their Derivatives
Suzuki, Hitomi,Yi, Qui,Inoue, Junko,Kusume, Kumiko,Ogawa, Takuji
, p. 887 - 890 (2007/10/02)
Copper(I) iodide-catalyzed reaction of aryl iodides with anion derived from phenylsulfonylacetonitrile in hot hexamethylphosphoric triamide affords α-arylated nitriles in good to moderate yields.Further alkylation of these nitriles followed by reductive removal of sulfonyl group provides a simple route to α-arylalkanenitriles.