85609-09-2

Usage

Uses

Used in Pharmaceutical Synthesis:
Benzene, 1-iodo-4-(2-methylpropyl)is utilized as an intermediate in the production of various pharmaceuticals. Its unique structure allows it to be a key component in the synthesis of drugs that target specific medical conditions, contributing to the development of new and effective treatments.
Used in Agrochemical Production:
Benzene, 1-iodo-4-(2-methylpropyl)also plays a role in the creation of agrochemicals, which are chemicals used in agricultural processes such as pest control and crop enhancement. Its application in this industry helps to improve agricultural yields and protect crops from harmful organisms.
Used in Organic Reactions as a Reagent:
Benzene, 1-iodo-4-(2-methylpropyl)functions as a reagent in a range of organic reactions, facilitating the synthesis of complex organic molecules. Its presence can drive reactions forward, enabling the formation of desired products in research and industrial settings.
Used in Research and Industrial Laboratories:
As a common component in laboratories focused on chemical research and development, Benzene, 1-iodo-4-(2-methylpropyl)is vital for conducting experiments and developing new chemical processes. Its versatility in reactions makes it a valuable asset in the pursuit of scientific discovery and innovation.
Safety Considerations:
Given the potential toxicity and harmful nature of Benzene, 1-iodo-4-(2-methylpropyl)-, it is crucial to handle Benzene, 1-iodo-4-(2-methylpropyl)- with care. Proper safety measures, including the use of personal protective equipment and adherence to laboratory safety protocols, are essential to minimize risks associated with its use.

Upstream product

• 15164-44-0 p-(iodophenyl)carboxaldehyde 
• 1332490-79-5 1-(4-iodophenyl)-2-methylpropan-1-ol 
• 538-93-2 1-phenyl-2-methylpropane 

Downstream Products

• 194606-12-7 2-tert-butyl-4,5-dihydro-5-(4-isobutylphenyl)-1,3-dioxepin 
• 40150-98-9 4-(2-methyl-1-propyl)benzaldehyde 
• 6448-12-0 ethyl 2-(4-isobutylphenyl)propenoate 
• 570368-33-1 1-isobutyl-4-[(1R,2E)-1-methyl-2-heptenyl]benzene 
• 194606-25-2 Acetic acid (S)-2-(4-isobutyl-phenyl)-3-(toluene-4-sulfonyloxy)-propyl ester 
• 194606-19-4 (2R)-(+)-3-acetoxy-2-(4-isobutylphenyl)-1-propanol 
• 194606-15-0 2-(4-isobutylphenyl)-1,3-propanediol 
• 194606-27-4 (-)-2-(4-isobutylphenyl)-1-acetoxypropane 
• 114937-30-3 (2S)-2-<4-(2-Methylpropyl)phenyl>propan-1-ol 
• 51146-56-6 (S)-ibuprofen 
• 112520-82-8 (4-isobutylphenyl)-(phenylsulfonyl)acetonitrile 
• 538-93-2 1-phenyl-2-methylpropane 

Relevant academic research and scientific papers

Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation

The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.

TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION

The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.

4-AMINO-5-OXO-7, 8-DIHYDROPYRIMIDO [5,4-F] [1,4] OXAZEPIN-6 (5H) -YL) PHENYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The invention provides compounds of Formula (I), wherein R1, R2a, R2b, R3, m and A are as defined herein, as well as compositions thereof and methods for treating a disease, condition or disorder that is modulated by the inhibition of the diacylglycerol O-acyltransferase 1 (DGAT-1) enzyme by administering the compounds of the present invention and/or compositions thereof.

4-AMINO-7,8-DIHYDROPYRIDO[4,3-d]PYRIMIDIN-5(6H)-ONE DERIVATIVES

The invention provides compounds of the general Formula (I) where R1, R2, and A are defined herein, as well as the preparation, compositions and uses thereof.

Lipase-mediated asymmetric construction of 2-arylpropionic acids: Enantiocontrolled syntheses of S-naproxen and S-ibuprofen

A general and enantiocontrolled synthetic route to 2-arylpropionic acids, represented by non-steroidal anti-inflammatory drugs S-naproxen 1a and S-ibuprofen 1b, has been developed by employing the lipase-mediated asymmetric acetylation of prochiral 2-aryl-1,3-propanediol 3, which has been derived via a Heck reaction, as the key step.