112529-80-3

Upstream product

• 103576-61-0 4(S)-methyl-5(R)-<1(S)-methyl-2-<(tert-butyldiphenylsilyl)oxy>ethyl>-dihydro-2(3H)furanone 
• 110410-93-0 3-carbomethoxy-4(S)-methyl-5(R)-<1(S)-methyl-2-<(tert-butyldiphenylsilyl)oxy>ethyl>dihydro-2(3H)-furanone 
• 115047-24-0 (4S,5R)-5-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-3-((E)-(S)-1,4-dimethyl-pent-2-enyl)-4-methyl-2-oxo-tetrahydro-furan-3-carboxylic acid methyl ester 
• 110455-56-6 3(S)-(1(S),4-dimethyl-2(E)-pentenyl)-4(S)-methyl-5(R)-<1(S)-methyl-2<(tert-butyldiphenylsilyl)oxy>ethyl>dihydro-2(3H)-furanone 
• 77-76-9 2,2-dimethoxy-propane 
• 115047-25-1 (E)-(2S,3S,4S,5S,6S)-1-(tert-Butyl-diphenyl-silanyloxy)-2,4,6,9-tetramethyl-dec-7-ene-3,5-diol 

Downstream Products

• 112452-64-9 6(S)-(1(S)-methyl-2-cyanoethyl)-4(S)-<1(S)-methyl-2-<(tert-butyldiphenylsilyl)oxy>ethyl>-2,2,5(S)-trimethyl-1,3-dioxane 
• 115047-26-2 (S)-3-{(4S,5S,6S)-6-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2,2,5-trimethyl-[1,3]dioxan-4-yl}-butyric acid 

Relevant academic research and scientific papers

A CHIRAL, NON-RACEMIC C1-C7 ERYTHRONOLIDE SYNTHON USING THE 3-METHYL-γ-BUTYROLACTONE STRATEGY

A chiral, non-racemic C1-C7 unit for the synthesis of the erythronolides has been prepared.R-3-Methyl-γ-butyrolactone serves as the template for the synthesis.The stereochemistry at C3 of the synthon 13 was established by stereoselective, kinetic protonation of the enolates of lactones 9 and 10.