112584-40-4

Basic information

• Product Name: 2-BROMO-5-METHOXYBENZENE-1-CARBOHYDRAZIDE
• Synonyms: 2-BROMO-5-METHOXYBENZENE-1-CARBOHYDRAZIDE;2-Bromo-5-methoxybenzohydrazide;2-Bromo-5-methoxybenzoic acid hydrazide
• CAS NO: 112584-40-4
• Molecular Formula: C₈H₉BrN₂O₂
• Molecular Weight: 245.07
• Mol File: 112584-40-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 165 °C
• Appearance: /
• Density: 1.559 g/cm³
• Refractive Index: 1.591
• Storage Temp.: Store Cold
• PKA: 11.48±0.10(Predicted)
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2-BROMO-5-METHOXYBENZENE-1-CARBOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-5-METHOXYBENZENE-1-CARBOHYDRAZIDE(112584-40-4)
• EPA Substance Registry System: 2-BROMO-5-METHOXYBENZENE-1-CARBOHYDRAZIDE(112584-40-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 112584-40-4(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-methoxybenzene-1-carbohydrazide is a chemical compound that contains a benzene ring with a bromine atom and a methoxy group attached. It also has a carbohydrazide functional group, which is a derivative of hydrazine. 2-BROMO-5-METHOXYBENZENE-1-CARBOHYDRAZIDE is commonly used in organic synthesis and pharmaceutical research as a building block for creating new molecules with potential biological activity. It may also have applications in the production of dyes and pigments due to its aromatic nature and potential reactivity. Due to its structure and functional groups, it has the potential to undergo various chemical reactions and can serve as a precursor for the synthesis of more complex compounds.

InChI:InChI=1/C8H9BrN2O2/c1-13-5-2-3-7(9)6(4-5)8(12)11-10/h2-4H,10H2,1H3,(H,11,12)

Upstream product

• 22921-68-2 2-bromo-5-methoxy-benzoic acid 
• 58733-41-8 5-methoxy-2-bromo benzoic acid ethyl ester 
• 35450-36-3 methyl 2-bromo-5-methoxybenzoate 

Downstream Products

• 1256575-02-6 (E)-N'-(3-(3,5,6-trichloropyridin-2-yloxy)benzylidene)-2-bromo-5-methoxybenzohydrazide 
• 131634-50-9 α-chloro-2-bromo-5-methoxybenzaldehyde-2-phenylsulfonylhydrazone 
• 1620752-75-1 methyl 7-methoxy-5-oxo-2-phenyl-1,5-dihydro-[1,2,4]triazolo[1,5-b]isoquinoline-10-carboxylate 
• 1372167-86-6 2-bromo-N'-[(1Z)-(4-hydroxy-3-methoxyphenyl)methylene]-5-methoxybenzohydrazide 
• 1372167-85-5 2-bromo-N'-[(1Z)-(4-hydroxyphenyl)methylene]-5-methoxybenzohydrazide 
• 1372167-84-4 2-bromo-N'-[(1Z)-(2-hydroxyphenyl)methylene]-5-methoxybenzohydrazide 
• 1372167-82-2 2-bromo-N'-[(1Z)-(4-fluorophenyl)methylene]-5-methoxybenzohydrazide 
• 1372167-81-1 2-bromo-5-methoxy-N'-[(1Z)-pyridin-3-yl methylene]benzohydrazide 
• 1372167-80-0 2-bromo-5-methoxy-N'-[(1Z)-(4-methylphenyl)methylene]benzohydrazide 
• 1372167-79-7 N'-[(1Z)-biphenyl-4-ylmethylene]-2-bromo-5-methoxybenzohydrazide 
• 1372167-78-6 2-bromo-5-methoxy-N'-[(1Z)-phenylmethylene]benzohydrazide 
• 1372167-77-5 2-bromo-5-methoxy-N'-[(1Z)-(4-nitrophenyl)methylene]benzohydrazide 
• 1372167-76-4 2-bromo-5-methoxy-N'-[(1Z)-(2-methoxyphenyl)methylene]benzohydrazide 
• 1372167-75-3 2-bromo-5-methoxy-N'-[(1Z)-(4-methoxyphenyl)methylene]benzohydrazide 

Relevant articles and documents

Synthesis of some bioactive 2-bromo-5-methoxy-N′-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives

Eight novel 2-bromo-5-methoxy-N′-[4-(aryl)-1,3-thiazol-2-yl]benzohydrazide derivatives were prepared and characterized by analytical and spectral analyses. All the compounds were screened for their analgesic, antifungal and antibacterial activities and th

An integration of condensation/Ullmann-type coupling/bicyclization sequences: Copper-catalyzed three-component direct synthesis of [1,2,4]triazolo[1,5-b]isoquinolin-5(1H)-ones

A highly efficient three-component domino protocol has been developed for the synthesis of [1,2,4]triazolo[1,5-b]isoquinolin-5(1H)-ones from simple and readily available o-halogenated benzohydrazides, aldehydes and nitriles. This domino process involves sequential selective condensation, copper-catalyzed intermolecular C-arylation and bicyclization. Notably, the use of ligands and anaerobic conditions can be avoided in this reaction.

Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles

Two new series of compounds namely, 3,6-disubstituted-1,2,4-triazolo[3,4-b] [1,3,4]thiadizoles (5a-j) and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4- b][1,3,4]thiadizoles (7a-j) were prepared. In continuation of a previously reported study, the firs