1126-07-4

Basic information

• Product Name: (R)-3-Phenyl-butan-1-ol
• Synonyms: (R)-3-Phenyl-butan-1-ol;(R)-3-Phenyl-butanol;(R)-γ-Methylhydrocinnamyl alcohol;[R,(-)]-3-Phenyl-1-butanol
• CAS NO: 1126-07-4
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.21756
• Mol File: 1126-07-4.mol
• Article Data: 36

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-3-Phenyl-butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-Phenyl-butan-1-ol(1126-07-4)
• EPA Substance Registry System: (R)-3-Phenyl-butan-1-ol(1126-07-4)

Safety Data

• Hazardous Substances Data: 1126-07-4(Hazardous Substances Data)

Usage

General Description

(R)-3-Phenyl-butan-1-ol, also known as (R)-3-hydroxy-1-phenylbutane, is a chiral alcohol compound with the molecular formula C10H14O. It is a colorless liquid with a floral and sweet aroma, often used in the manufacturing of various fragrances and flavors. (R)-3-Phenyl-butan-1-ol is primarily derived from natural sources such as plants and flowers, and it is used in many consumer products including perfumes, colognes, and air fresheners. In addition to its aromatic properties, (R)-3-Phenyl-butan-1-ol also has potential applications in the pharmaceutical and chemical industries, making it a versatile and valuable chemical compound.

Upstream product

• 1134-71-0 ethyl 3-phenylbutanoate 
• 75492-29-4 (+)-(S)-methyloxetane 
• 71-43-2 benzene 
• 16251-77-7 3-Phenylbutyraldehyde 
• 917-54-4 methyllithium 
• 54976-37-3 3-phenylbut-2-en-1-ol 
• 46319-71-5 3-phenyl-1-butyl acetate 
• 42307-58-4 3-phenylbutanal 
• 1196-67-4 (E)-β-methylcinnamaldehyde 
• 98-86-2 acetophenone 
• 54976-38-4 (E)-3-phenylbut-2-en-1-ol 
• 19352-10-4 2-methyl-2-phenyloxetane 
• 704-80-3 (E)-3-phenyl-2-butenoic acid 
• 1196-67-4 3-phenyl-2-butenal 

Downstream Products

• 27798-98-7 (-)(R)-4-bromo-2-phenyl-butane 
• 36617-72-8 (-)-(R)-1-Chlor-2-phenyl-butan 
• 135-98-8 (2R)-sec-butylbenzene 
• 1018670-09-1 5-acetyl-6-hydroxy-4-methyl-7-[3-R-(3-(phenyl)butoxy)]benzofuran 
• 22800-20-0 (-)-R-5-Phenylhexansaeure 
• 36617-83-1 (-)-R-N,N-Dimethyl-5-phenylhexanamid 
• 36617-82-0 (-)-(R)-N,N-dimethyl-4-phenylpentanamide 
• 36617-86-4 (-)-R-N,N-Dimethyl-5-phenylhexylamin 
• 36617-85-3 (-)-R-N,N-Dimethyl-4-phenylpentylamin 
• 36617-92-2 (-)-R-5-Phenyl-1-hexen 
• 36667-55-7 (-)-2-phenylpentane 
• 36617-91-1 (R)-pent-4-en-2-ylbenzene 
• 16433-43-5 (R)-4-phenylpentanoic acid 
• 6031-02-3 (2R)-hexan-2-ylbenzene 

Relevant articles and documents

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Enantioselective β-Protonation of Enals via a Shuttling Strategy

Remote asymmetric protonation is a longstanding challenge due to the small size of protons. Reactions involving electron-deficient olefins pose a further difficulty due to the electrophilic nature of these substrates. We report a shuttling system that delivers a proton in a highly enantioselective manner to the β-carbon of enals using a chiral N-heterocyclic carbene (NHC) catalyst. Choices of a Br?nsted base shuttle and a Br?nsted acid cocatalyst are critical for highly stereoselective β-protonation of the homoenolate intermediate and regeneration of the NHC catalyst results in functionalization of the carbonyl group. Thioesters with a β-chiral center were prepared in a redox-neutral transformation with an excellent yield and ee.

Asymmetric Umpolung Hydrogenation and Deuteration of Alkenes Catalyzed by Nickel

Nickel-catalyzed asymmetric hydrogenation of several types of alkenes proceeds in high enantioselectivity, using acetic acid or water as the hydrogen source and indium powder as electron donor. The scope of alkenes herein include α,β-unsaturated esters, n

Enantioselective Hydrogenation of β,β-Disubstituted Unsaturated Carboxylic Acids under Base-Free Conditions

An additive-free enantioselective hydrogenation of β,β-disubstituted unsaturated carboxylic acids catalyzed by the Rh-(R,R)-f-spiroPhos complex has been developed. Under mild conditions, a wide scope of β,β-disubstituted unsaturated carboxylic acids were hydrogenated to the corresponding chiral carboxylic acids with excellent enantioselectivities (up to 99.3% ee). This methodology was also successfully applied to the synthesis of the pharmaceutical molecule indatraline.