112639-04-0

Basic information

• Product Name: Benzene, 2,4-dibromo-1,5-dimethoxy-3-pentyl-
• CAS NO: 112639-04-0
• Molecular Formula: C13H18Br2O2
• Molecular Weight: 366.093
• Mol File: 112639-04-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 2,4-dibromo-1,5-dimethoxy-3-pentyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2,4-dibromo-1,5-dimethoxy-3-pentyl-(112639-04-0)
• EPA Substance Registry System: Benzene, 2,4-dibromo-1,5-dimethoxy-3-pentyl-(112639-04-0)

Safety Data

• Hazardous Substances Data: 112639-04-0(Hazardous Substances Data)

Upstream product

• 22976-40-5 1,3-dimethoxy-5-pentylbenzene 
• 38228-29-4 1,3-dimethoxy-5-(pent-1-en-1-yl)benzene 
• 52189-65-8 olivetol carboxylic acid dimethyl ether 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 

Downstream Products

• 13956-29-1 CBD 
• 78463-34-0 4,6-dibromo-5-pentylbenzene-1,3-diol 

Relevant articles and documents

Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB2Receptor Derived from the Natural Product Cannabidiol

Cannabidiol (CBD), the second most abundant of the active compounds found in the Cannabis sativa plant, is of increasing interest because it is approved for human use and is neither euphorizing nor addictive. Here, we design and synthesize novel compounds taking into account that CBD is both a partial agonist, when it binds to the orthosteric site, and a negative allosteric modulator, when it binds to the allosteric site of the cannabinoid CB2 receptor. Molecular dynamic simulations and site-directed mutagenesis studies have identified the allosteric site near the receptor entrance. This knowledge has permitted to perform structure-guided design of negative and positive allosteric modulators of the CB2 receptor with potential therapeutic utility.

Halogenation of Phenols and Phenyl Ethers with Potassium Halides in the Presence of 18-Crown-6 on Oxidation with m-Chloroperbenzoic Acid

Several types of phenyl ethers have been monobrominated in the ring in good yields with potassium bromide in the presence of 18-crown-6 on oxidation with m-chloroperbenzoic acid.Monoiodination takes place with both phenyl ethers and free phenols when potassium iodide is employed.