1126433-33-7Relevant academic research and scientific papers
CITU: A Peptide and Decarboxylative Coupling Reagent
Degruyter, Justine N.,Malins, Lara R.,Wimmer, Laurin,Clay, Khalyd J.,Lopez-Ogalla, Javier,Qin, Tian,Cornella, Josep,Liu, Zhiqing,Che, Guanda,Bao, Denghui,Stevens, Jason M.,Qiao, Jennifer X.,Allen, Martin P.,Poss, Michael A.,Baran, Phil S.
supporting information, p. 6196 - 6199 (2017/11/24)
Tetrachloro-N-hydroxyphthalimide tetramethyluronium hexafluorophosphate (CITU) is disclosed as a convenient and economical reagent for both acylation and decarboxylative cross-coupling chemistries. Within the former set of reactions, CITU displays reactiv
Benzotriazole-assisted solid-phase assembly of Leu-Enkephalin, amyloid β segment 34-42, and other "difficult" peptide sequences
Katritzky, Alan R.,Haase, Danniebelle N.,Johnsons, Jodie V.,Chung, Alfred
supporting information; experimental part, p. 2028 - 2032 (2009/08/07)
Microwave-assisted solid-phase syntheses of six "difficult" peptides, H-VVSVV-NH2 (3), H-VVVSVV-NH2(4), H-VIVIG-OH (5), H-TVTVTV-NH2 (6), H-VKDGYI-NH2 (7), and H-VKDVYI-NH2 (8), were achieved utilizing N-(Fmoc-α-aminoacyl) benzotriazoles. Extension to the syntheses of Leu-enkephalin (9) and amyloid-β (34-42) (10) demonstrates that this strategy comprises an efficient route to new and known "difficult" peptides.
