112649-54-4

Upstream product

• 106920-99-4 1-(3-hydroxy-6,7,8,9-tetrahydrodibenzofuran-2-yl)-ethanone 
• 100-52-7 benzaldehyde 
• 1233321-97-5 C₂₁H₁₈O₃ 
• 112649-51-1 7-(2-Oxocyclohexyloxy)-2-phenyl-4H-1-benzopyran-4-one 
• 1056477-06-5 2-bromocyclohexanone 
• 112649-53-3 6,7,8,9-tetrahydro-2-phenyl-4H-benzofuro<3,2-g><1>benzopyran-4-one 
• 6665-86-7 7-hydroxyflavone 

Relevant academic research and scientific papers

One-pot synthesis of furoflavanones

Several new furoflavanones (5-7) have been synthesized from hydroxy acetyl benzofuran and an aryl aldehyde in presence of piperidine. These furoflavanones were dehydrogenated to furoflavones (8-10) using DDQ (2,3-dichloro-5,6-dicyano- 1,4-benzoquinone). The chalcone synthesized (4b) using 1% ethanolic sodium hydroxide from hydroxy acetyl benzofuran and aryl aldehyde shows promising antiinflammatory activity.

A New and Convenient Synthesis of Benzofuroflavones

A new and convenient synthesis of benzofuroflavones has been achieved by the condensation of 2-bromocyclohexanone with hydroxyflavones followed by ring closure with PPA and subsequent dehydrogenation using DDQ.