1126623-89-9 Usage
Uses
Used in Pharmaceutical Industry:
AG 013736-d3 is used as a tyrosine kinase inhibitor for cancer therapy. It targets and inhibits specific tyrosine kinases, which are often overactive in cancer cells, leading to uncontrolled cell growth and tumor formation. By inhibiting these enzymes, AG 013736-d3 can help slow down or stop the progression of cancer.
Used in Cancer Research:
AG 013736-d3 is also used as a research tool in the field of cancer biology. Its labeled nature allows researchers to study the mechanisms of action of Axitinib and other tyrosine kinase inhibitors, as well as investigate the role of tyrosine kinases in cancer development and progression. This can lead to the discovery of new therapeutic targets and the development of more effective cancer treatments.
Used in Drug Development:
AG 013736-d3 serves as a valuable compound in the development of new drugs targeting tyrosine kinases. By understanding its interactions with these enzymes and its effects on cancer cells, researchers can design and synthesize novel compounds with improved potency, selectivity, and reduced side effects. This can ultimately lead to the development of more effective cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 1126623-89-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,6,6,2 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1126623-89:
(9*1)+(8*1)+(7*2)+(6*6)+(5*6)+(4*2)+(3*3)+(2*8)+(1*9)=139
139 % 10 = 9
So 1126623-89-9 is a valid CAS Registry Number.
1126623-89-9Relevant academic research and scientific papers
METHOD FOR SYNTHESIS OF DEUTERATED AMIDE AND DEUTERATED SULFONAMIDE
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, (2021/04/23)
A novel method for synthesizing deuterated amides and deuterated sulfonamides includes the following steps: (1) adding a compound M, DMAP, R3—X to a solvent to obtain a compound N after a reaction is complete; and (2) adding the compound N, Rs
Deuterated compound and application thereof in treatment of cancer
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Paragraph 0129; 0135, (2021/03/06)
The present invention relates to a deuterated compound and application thereof in the treatment of cancer. Specifically, the present invention provides the compound of formula (I) and pharmaceuticallyacceptable salt or ester thereof, and a pharmaceutical composition thereof. The compound and the pharmaceutical composition are used for inhibiting or regulating the activity of tyrosine kinase and treating disease symptoms or symptoms including cancer mediated by tyrosine kinase.
