112672-52-3

Upstream product

• 64-17-5 ethanol 
• 53744-76-6 N-phenylthiocarbamoylacetonitrile 
• 28663-68-5 ethyl (phenylhydrazono)chloroacetate 
• 28663-68-5 ethyl chloro(2-phenylhydrazono)acetate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 103-72-0 phenyl isothiocyanate 
• 7357-70-2 Cyanothioacetamide 
• 69015-65-2 3-(aminothioxomethyl)-2H-chromen-2-one 

Relevant academic research and scientific papers

Reactions of hydrazonoyl halides 391: Synthesis of some new triazoles and 2,3-dihydro-1,3,4-thiadiazoles

C-acyl-N-phenyllhydrazonoyl halides 1a-g have been caused to react with 3-(aminomethylthiomethyl)-2H-chromen-2-one in the presence of triethylamine to give triazoles. Also, C-acyl-N-pyrazolylhydrazonoyl chlorides 13a,b react with alkyl carbodithioates (14 or 15)a-m afforded 2,3-dihydro-1,3,4-thiadiazoles in good yields. Structures of the new compounds were elucidated on the basis of elemental analyses, spectral data, and alternative methods of synthesis whenever possible.

The reaction of N-R-2-cyanothioacetamides with ethyl[(aryl)hydrazono] chloroacetates

Depending on the nature of the substituents in the starting reagents and the basicity of the medium the cyclization of N-R-2-cyanothioacetamides with ethyl [(aryl)hydrazono]chloroacetates gives 3-aryl-2-cyanomethylidene-5- ethoxycarbonyl-1,3,4-thiadiazoles, 5-arylhydrazono-2-cyanomethylidene-3-phenyl- thiazolidin-4-ones, di[(aryl)hydrazono](ethoxycarbonylmethyl) sulfides, and 5-amino-3-cyano-2-phenyl-amino-4-(N-phenylaminothiocarbonyl)thiophene.

Cyclodesulfurization of Substituted Thiosemicarbazides into 1,3,4-Oxadiazoles via Hydrazonoyl Chlorides

The reaction of thiosemicarbazides 1a-h with hydrazonoyl chlorides 2a-g at ambient temperature, in the presence of triethylamine yielded, in each case, two products. The structure of these compounds was confirmed as 1,3,4-oxadiazoles 14a-h and hydrazonoth

Synthesis of 2,3-Dihydro-1,3,4-thiadiazole, Thiazole, and Triazolo[4,3-a]pyrimidine Derivatives from Ethyl Benzoylacetate

Thiophene and thiazole derivatives can be obtained from potassium salt of ethyl 3-oxo-3-phenyl-2-[(phenylamino)thioxomethyl]propanoate and ethyl chloroacetate in N,N-dimethylformamide solution under different conditions. 2,3-Dihydro-1,3,4-thiadiazoles and triazolo[4,3-a]pyrimidine were obtained from reaction of hydrazonoyl halides with each of thioanilide and pyrimidine-2-thione, respectively. Structures of the newly synthesized compounds were elucidated on the basis of elemental analysis, spectral data, and alternative synthesis route whenever possible.

Reactions of hydrazonoyl halides 331: Synthesis of some new 2,3-dihydro-1,3,4-thiadiazoles containing pyrazol-3-yl, indolin-2-one-2-yl and indan-1,3-dione-2-yl moieties

Some new 2,3-dihydro-1,3,4-thiadiazoles containing pyrazol-3-yl, indolin-2-one-2-yl and indan-1,3-dione-2-yl moieties in a good yields obtained from the reaction of hydrazonoyl halides with thiocarbamate and carbodithioate in ethanolic triethylamine respe

Reactions with Hydrazonoyl Halides. Part 10. Formation of Thiohydrazide, Hydrazonoyl Sulfide and Arylazothiazole Derivatives

Hydrazonoyl halides react with α-thiocarbamoylcinnamonitrile derivatives, under alkaline conditions, to afford thiohydrazide (4), hydrazonoyl sulfide (7a,b) or arylazothiazole derivatives (9a,b), depending on the nature of the hydrazonoyl halide; a sequence leading to the formation of these products is discussed.

REACTIONS WITH HYDRAZIDOYL HALIDES. IX. A NOVEL SYNTHESIS OF SOME HYDRAZIDOYL SULFIDES, THIADIAZOLINES, THIAZOLES AND COUMARINES

The reactions of hydrazidoyl halides with N-phenylcyanothioacetamide and α-cyanothioacetamide gave unexpected hydrazidoyl sulfides, thiadiazolines and thiazole derivatives.The structures of these products were confirmed by elemental analyses and spectral data and wherever possible, alternate synthesis.Key words: Hydrazidoyl sulfides, thiadiazolines; thiazoles; coumarines; hydrazidoyl halides; N-phenylcyanothiacetamide.