112723-89-4

Usage

Derivative of

Indole

Class of organic compounds

Indoles

Physical state at room temperature

White to light brown solid

Uses

Production of pharmaceuticals and agrochemicals

Potential biological activities

Anticancer, anti-inflammatory, and antiviral properties

Applications

Medicinal and agricultural fields

Upstream product

• 88530-86-3 5-methoxy-2,3-diphenyl-1H-indole 
• 501-65-5 diphenyl acetylene 
• 54049-23-9 4-hydroxyphenylhydrazine hydrochloride 
• 123-30-8 4-amino-phenol 
• 104-94-9 4-methoxy-aniline 
• 119-53-9 2-hydroxy-2-phenylacetophenone 

Downstream Products

• 191348-83-1 5-hydroxy-2,3-diphenyl-1H-indole-6-carbaldehyde 
• 127473-42-1 2,3-diphenyl-5-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranosyloxy>indole 
• 127473-40-9 2,3-diphenyl-5-(2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosyloxy)indole 

Relevant academic research and scientific papers

Regioselective synthesis of indoles via rhodium-catalyzed C-H activation directed by an in-situ generated redox-neutral group

A regioselective synthesis of indoles from arylhydrazine hydrochlorides with alkynes and diethyl ketone catalyzed by a rhodium complex is described. A possible mechanism involving an in-situ generated oxidizing directing group -N-Ni'CR1R2 assisted ortho-C-H activation and reductive elimination are proposed. The catalytic reaction is highly compatible with a wide range of functional arylhydrazines and alkynes. The reaction proceeds under mild reaction conditions and is atom-step economical.

Indole compounds and their use as estrogen agonists/antagonists

This invention relates to compounds, in particular indoles, that are useful as estrogen agonists and antagonists and pharmaceutical uses thereof. The present invention also relates to indoles that are selective for the ERβ receptor and pharmaceutical uses

Glycosylation of 2,3-Diphenylindole and Derivatives - Synthesis of O-, N-, and C-Glycopyranosides

Reaction of different glycosyl donors with 5-hydroxy-N-methyl-2,3-diphenylindole (1C) led only to O-glycosylation compounds 6a - c and 8c-α,β).Depending on the O-protection of the glycosyl donors (2a - c, 3b, 4c), the β-products were obtained mainly or e