112724-02-4

Basic information

• Product Name: 1-Ethyl-6-methoxy-2,3-diphenyl-1H-indole
• Synonyms: 1-Ethyl-6-methoxy-2,3-diphenyl-1H-indole
• CAS NO: 112724-02-4
• Molecular Weight: 327.426
• Mol File: 112724-02-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Ethyl-6-methoxy-2,3-diphenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Ethyl-6-methoxy-2,3-diphenyl-1H-indole(112724-02-4)
• EPA Substance Registry System: 1-Ethyl-6-methoxy-2,3-diphenyl-1H-indole(112724-02-4)

Safety Data

• Hazardous Substances Data: 112724-02-4(Hazardous Substances Data)

Upstream product

• 53142-27-1 C₁₁H₁₇NO₂ 
• 501-65-5 diphenyl acetylene 
• 14292-85-4 6-methoxy-2,3-diphenyl-1H-indole 
• 75-03-6 ethyl iodide 

Relevant articles and documents

Rhodium-catalyzed annulation of tertiary aniline N-oxides to N-alkylindoles: Regioselective C-H activation, oxygen-atom transfer, and N-dealkylative cyclization

[Cp?RhIII]-catalyzed annulation of tertiary aniline N-oxides with alkynes was reported to achieve the challenging ortho C-H functionalization of tertiary anilines via N-O bond acting as a traceless directing group. More significantly, this system represents the first example which integrates C-H activation, oxygen-atom transfer, and N-dealkylative cyclization in one reaction. This unprecedented coupling reaction has allowed the construction of N-alkylindole derivatives in high efficiency with broad substrate scope and good functional group tolerance.