112754-67-3Relevant academic research and scientific papers
Reactivite de la trifluoro-1,1,1 propanone dans des conditions reactionelles de type Friedel-Crafts: nouvel exemple de chloroalkylation
Bonnet-Delpon, Daniele,Charpentier-Morize, Micheline
, p. 933 - 936 (2007/10/02)
In the presence of one equivalent of AlCl3, the 1,1,1-trifluoro propanone 1 reacts with benzene or toluene to give 1,1,1-trifluoro-2-aryl-2-chloro propanes 4 in relatively good yield, by a new chloroalkylation reaction.This is the first example of an addition of an aromatic compound onto an aliphatic trifluoromethyl ketone.
