112764-72-4

Upstream product

• 38880-89-6 N-(2-hydroxy-4-nitrophenyl)benzamide 
• 100-39-0 benzyl bromide 
• 121-88-0 5-Nitro-2-aminophenol 
• 25945-96-4 2-benzyloxy-4-nitro-phenylamine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 112764-73-5 N-(4-Amino-2-benzyloxy-phenyl)-benzamide 
• 112764-65-5 1-benzoyl-7-(benzyloxy)-4-bromo-3-methyl-N⁵-(phenylsulfonyl)-5-(2-propyn-1-ylamino)indole 
• 112764-66-6 6-benzoyl-5-(benzyloxy)-1,2-dihydro-1-(hydroxymethyl)-8-methyl-3-(phenylsulfonyl)-3H-pyrrolo<3,2-e>indole 
• 112793-55-2 6-benzoyl-5-(benzyloxy)-1,2-dihydro-8-methyl-1-methylidene-3-(phenylsulfonyl)-3H-pyrrolo<3,2-e>indole 
• 112764-64-4 5-amino-1-benzoyl-7-(benzyloxy)-4-bromo-3-methyl-N⁵-(phenylsulfonyl)indole 
• 112764-67-7 (1RS)-3-(Benzenesulfonyl)-5-(benzyloxy)-1-(hydroxymethyl)-8-methyl-1,2-dihydro-3H-pyrrolo<3,2-e>indole 
• 175614-07-0 (+/-)-(1R*)-5-(benzyloxy)-3-<(tert-butyloxy)carbonyl>-1-(chloromethyl)-8-methyl-1,2-dihydro-3H-pyrrolo<3,2-e>indole 
• 112089-71-1 (+/-)-(1R*)-5-(benzyloxy)-3-<(tert-butyloxy)carbonyl>-1-(hydroxymethyl)-8-methyl-1,2-dihydro-3H-pyrrolo<3,2-e>indole 
• 112793-56-3 (1RS)-3-Benzenesulfonyl-5-hydroxy-1-hydroxymethyl-8-methyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole 
• 112089-37-9 1,2,8,8a-tetrahydro-7-methyl-2-(phenylsulfonyl)cyclopropa-pyrrolo<3,2-e>indol-4(5H)-one 
• 112243-83-1 5-(benzyloxy)-1,2,3,6-tetrahydro-8-methylbenzo<1,2-b:4,3-b'>dipyrrole-1-methanol 
• 115017-06-6 [6-Benzenesulfonyl-4-benzyloxy-8-(1,2-dihydroxy-ethyl)-1-methyl-7,8-dihydro-6H-pyrrolo[3,2-e]indol-3-yl]-phenyl-methanone 
• 114996-69-9 6-benzoyl-5-(benzyloxy)-1,2-dihydro-8-methyl-3-(phenylsulfonyl)-1-vinyl-3H-pyrrolo<3,2-e>indole 
• 112764-74-6 N-(4-Benzenesulfonylamino-2-benzyloxy-phenyl)-benzamide 

Relevant academic research and scientific papers

Novel sulfonanilide analogs decrease aromatase activity in breast cancer cells: Synthesis, biological evaluation, and ligand-based pharmacophore identification

Aromatase converts androgens to estrogens and is a particularly attractive target in the treatment of estrogen receptor positive breast cancer. Previously, the COX-2 selective inhibitor nimesulide and analogs decreased aromatase expression and enzyme acti

SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS

Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloakyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alk