112778-92-4

Upstream product

• 19429-87-9 α,α-diethoxy-N,N-dimethylbenzenemethanamine 
• 98-86-2 acetophenone 
• 145930-94-5 N,N-dimethyl-S-phenacylthiobenzimidium bromide 
• 30388-25-1 [Tris(dimethylamino)methyl]benzol 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 107553-43-5 2,4-diphenylbenzimidazo<1,2-a>pyrimidine 

Relevant academic research and scientific papers

New reaction of thiocarbonyl ylides. Interaction of S-alkyl-N,N-dimethylthiobenzimidium salts with activated acetylene derivatives leading to (E,E)-divinyl sulfides

The reaction of thiocarbonyl ylides with activated acetylene derivatives gives (E,E)-divinyl sulfides in good yields. The reaction mechanism is discussed and evidence in favor of the formation of a thiirane intermediate is presented.

Orthoamides, LVIII. Condensation reactions of CH2-acidic compounds with orthoamides of carboxylic acids and alkyne carboxylic acids

The orthoamide derivatives 1s and 2e were prepared from the guanidinium salt 7a and the appropriate carbanions. Cleavage of the orthoamide 2e with benzoyl chloride affords the amidinium salt 10a, which can be transformed into the amidinium salt 10b by an

STUDY OF THE ESCHENMOSER SULFIDE CONTRACTION METHOD WITH AND WITHOUT A THIOPHILE

Results obtained and observations made by applying the title method for the synthesis of enaminones 5a-o, using triphenylphosphine as a thiophile and triethylamine as a base, are reported.The product distributions of the deprotonations of α-phenacylthio iminium bromides with and without thiophile and those known from thiouronium and heterocyclic thionium analogs are compared.Key words: Enaminones; α-phenacylthio iminium bromides; disulfides; thiiranes.

A Simple Regioselective Synthesis of Pyrimidobenzimidazoles

2-Aminobenzimidazoles were reacted with enaminones in acetic acid to give pyrimidobenzimidazoles.With a substituted enaminone only one regioisomer was obtained.Structural assignments based on nmr and uv spectroscopy are presented.Possible pathways