112795-79-6

Upstream product

• 118431-79-1 2-[(3-nitrophenyl)methylene]-3-oxobutanoic acid,1-methylethyl ester 
• 17356-08-0 thiourea 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 64741-01-1 m-chloroperoxybenzoic acid 
• 108931-52-8 1,4-Dihydro-2-methoxy-6-methyl-4-(3-nitrophenyl)-5-pyrimidinecarboxylic acid,1-methylethyl ester 
• 119126-26-0 1-[(dimethylamino)carbonyl]-1,6-dihydro-2-methoxy-4-methyl-6-(3-nitrophenyl)-5-pyrimidinecarboxylic acid,1-methylethyl ester 

Relevant academic research and scientific papers

Highly versatile solid phase synthesis of biofunctional 4-aryl-3,4- dihydropyrimidines using resin-bound isothiourea building blocks and multidirectional resin cleavage

A series of pharmacologically active, functionalized 4-aryl-3,4- dihydropyrimidine-5-carboxylates (DHPMs) are prepared by a versatile novel solid phase approach. In the key step, a polymer-bound thiouronium salt is condensed with unsaturated β-ketoesters. The resulting polymer bound 1,4- dihydropyrimidines are cleaved from the resin employing multidirectional resin cleavage strategies.

1,2,3,4-Tetrahydro-6-substituted-4-aryl(or heterocyclo)-3-((substituted amino)carbonyl)-2-thioxo (or oxo)-5-pyrimidinecarboxylic acids and esters

Cardiovascular activity is exhibited by compounds having the formula STR1 and pharmaceutically acceptable salts thereof wherein X is oxygen or sulfur; R is hydrogen, alkyl, cycloalkyl, aryl, or arylalkyl and R1 is hydrogen, alkyl, cycloalkyl, a