108931-52-8

Upstream product

• 119144-83-1 2-amino-1,6-dihydro-4-methyl-6-(3-nitrophenyl)-1-(phenylsulfonyl)-5-pyrimidinecarboxylic acid ethyl ester 
• 118431-79-1 2-[(3-nitrophenyl)methylene]-3-oxobutanoic acid,1-methylethyl ester 
• 29427-58-5 O-methylisourea hemisulfate 

Downstream Products

• 123486-12-4 2-methoxy-4-methyl-6-(3-nitrophenyl)-1,5(6H)-pyrimidinedicarboxylic acid 5-(1-methylethyl) 1-(4-nitrophenyl) diester 
• 128162-86-7 (4R)-1,4-dihydro-2-methoxy-6-methyl-4-(3-nitrophenyl)-5-pyrimidinecarboxylic acid 1-methylethyl ester 
• 128162-87-8 (4S)-1,4-dihydro-2-methoxy-6-methyl-4-(3-nitrophenyl)-5-pyrimidinecarboxylic acid 1-methylethyl ester 
• 112770-77-1 (4R)-1,4-dihydro-2-<<(4-methoxyphenyl)methyl>thio>-6-methyl-4-(3-nitrophenyl)-5-pyrimidinecarboxylic acid 1-methylethyl ester 
• 112770-80-6 (4S)-1,4-dihydro-2-<<(4-methoxyphenyl)methyl>thio>-6-methyl-4-(3-nitrophenyl)-5-pyrimidinecarboxylic acid 1-methylethyl ester 
• 113094-77-2 <1(R)>-1,6-dihydro-2-methoxy-4-methyl-6(R)-(4-nitrophenyl)-1-<<(1-phenylethyl)amino>carbonyl>-5-pyrimidine carboxylic acid 1-methylethyl ester 
• 113116-81-7 <1(R)>-1,6-dihydro-2-methoxy-4-methyl-6(S)-(4-nitrophenyl)-1-<<(1-phenylethyl)amino>carbonyl>-5-pyrimidine carboxylic acid 1-methylethyl ester 
• 108931-62-0 2-methoxy-4-methyl-6-(3-nitrophenyl)-1,5(6H)-pyrimidinedicarboxylic acid, 1-[1-(phenylmethyl)-4-piperidinyl]5-(1-methylethyl) ester 
• 108931-60-8 2-methoxy-4-methyl-6-(3-nitrophenyl)-1,5(6H)-pyrimidinedicarboxylic acid, 5-(1-methylethyl) 1-[2-[methyl(phenylmethyl)amino]ethyl]ester 
• 123485-96-1 3,6-dihydro-4-methyl-6-(3-nitrophenyl)-2-0x0-1,5(2H)-pyrimidinedicarboxylic acid 5-(1-methylethyl) 1-(4-nitrophenyl) diester 
• 108930-68-3 1,5-diisopropyl 4-methyl-6-(3-nitrophenyl)-2-oxo-2,3-dihydro-pyrimidine-1,5(6H)-dicarboxylate 
• 112795-82-1 1,2,3,4-Tetrahydro-6-methyl-3-[(methylamino)carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester 
• 112795-85-4 1,2,3,4-Tetrahydro-6-methyl-3-[[(1-methylethyl)amino]carbonyl]-4-(3-nitrophenyl)-2-oxo-5-pyrimidinecarboxylic acid, 1-methylethyl ester 

Relevant academic research and scientific papers

2-thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters

Pyrimidine compounds of the formula STR1 wherein X is sulfur or oxygen, Y is R11 or --O--R1, and R4 is aryl or heterocyclo are disclosed. These compounds are useful as cardiovascular agents, particularly anti-hypertensive

3-oxo-1,2,4-triazolo(4,3-A) pyrimidine-6-carboxylic acid esters

Compounds having the formula STR1 and pharmaceutically acceptable salts thereof, wherein R4 is aryl are disclosed. These novel compounds are useful, for example, as cardiovascular agents.

1,2,3,4-Tetrahydro-6-substituted-4-aryl(or heterocyclo)-3-((substituted amino)carbonyl)-2-thioxo (or oxo)-5-pyrimidinecarboxylic acids and esters

Cardiovascular activity is exhibited by compounds having the formula STR1 and pharmaceutically acceptable salts thereof wherein X is oxygen or sulfur; R is hydrogen, alkyl, cycloalkyl, aryl, or arylalkyl and R1 is hydrogen, alkyl, cycloalkyl, a

Dihydropyrimidine carboxylic acid esters

Pyridine compounds of the formula STR1 wherein R4 is aryl or heterocyclo are disclosed. These compounds are useful as cardiovascular agents due to their calcium entry blocking vasodilator activity.

1,2,3,4-tetrahydro-6-substituted-4-aryl-3-substituted-2-thioxo(or oxo)-5-pyrimidinecarboxylic acids and esters and use thereof to lower blood pressure

Cardiovascular activity is exhibited by compounds having the formula STR1 and pharmaceutically acceptable salts thereof wherein X is oxygen or sulfur; R1 is alkyl, cycloalkyl, alkenyl, alkynyl, aryl --(CH2)n --Y2/sub