112816-32-7

Basic information

• Product Name: (R)-N-(2-toluenosulfonylamino-1-methyl-ethyl)-toluenesulfonamide
• Synonyms: (R)-N-(2-toluenosulfonylamino-1-methyl-ethyl)-toluenesulfonamide
• CAS NO: 112816-32-7
• Molecular Weight: 382.505
• Mol File: 112816-32-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-N-(2-toluenosulfonylamino-1-methyl-ethyl)-toluenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-(2-toluenosulfonylamino-1-methyl-ethyl)-toluenesulfonamide(112816-32-7)
• EPA Substance Registry System: (R)-N-(2-toluenosulfonylamino-1-methyl-ethyl)-toluenesulfonamide(112816-32-7)

Safety Data

• Hazardous Substances Data: 112816-32-7(Hazardous Substances Data)

Upstream product

• 75-09-2 dichloromethane 
• 19777-66-3 (R)-propane-1,2-diamine dihydrochloride 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 532400-61-6 (R)-6,6-difluoro-2-methyl-1,4-bis(toluene-4-sulfonyl)-[1,4]diazepane 
• 532400-60-5 (R)-2-methyl-1,4-bis(toluene-4-sulfonyl)-[1,4]diazepan-6-one 

Relevant articles and documents

Synthesis of 6,6-difluorohomopiperazines via microwave-assisted detosylation

[1,4]-Diazepan-6-ols are easily oxidized to ketones using Swern or Dess-Martin oxidation conditions. The fluorination of these [1,4]-diazepanones with diethylaminosulfur trifluoride (DAST) affords gem-difluorohomopiperazines. Detosylation under microwave conditions represents a rapid method to access the corresponding amines in high yields.

Methods of preparing manganese complexes of nitrogen-containing macrocyclic ligands

The present invention is directed to low molecular weight mimics of superoxide dismutase (SOD) represented by the formula: STR1 wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, and R'9 and X, Y, Z and n are as defined herein, useful as therapeutic agents for inflammatory disease states and disorders, ischemic/reperfusion injury, stroke, atherosclerosis, hypertension and all other conditions of oxidant-induced tissue damage or injury.