112896-90-9

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 32462-30-9 (S)-hydroxyphenylglycine 
• 69651-48-5 N-tert-butyloxycarbonyl-L-4-hydroxyphenylglycine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 112896-85-2 (R)-3-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{[(S)-2-((E)-(2S,6R,8S)-8-methoxymethoxy-2,4,6-trimethyl-non-4-enoylamino)-propionyl]-methyl-amino}-propionylamino)-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-propionic acid tert-butyl ester 
• 161722-18-5 (2S,4E,6R,8S)-8-tert-butyldimethylsilyloxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 161722-19-6 (2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine ρ-lactone 
• 161722-15-2 (2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine 
• 161722-17-4 N-tert-butoxycarbonyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 161722-16-3 (S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 112896-94-3 N-tert-butyoxycarbonyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 112896-83-0 N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 112896-92-1 N-tert-butoxycarbonyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 112896-93-2 O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-but 
• 119717-37-2 jasplakinolide 
• 112896-91-0 (S)-N-tert-butoxycarbonyl-4-tert-butyldimethylsilyloxy-α-diazoacetylbenzylamine 

Relevant academic research and scientific papers

Studies on the Novel Cyclodepsipeptides. A Total Synthesis of (+)-Jasplakinolide (Jaspamide)

Diastereocontrolled total synthesis of (+)-jasplakinolide (1) has been accomplished via coupling of the tetrapropionate-derived segment (9) with the tripeptide (10) followed by trichlorobenzoyl chloride-mediated macrolactonization.