112896-94-3

Basic information

• Product Name: N-tert-butyoxycarbonyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester
• Synonyms: N-tert-butyoxycarbonyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester
• CAS NO: 112896-94-3
• Molecular Weight: 730.815
• Mol File: 112896-94-3.mol

Chemical Properties

• CAS DataBase Reference: N-tert-butyoxycarbonyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-butyoxycarbonyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester(112896-94-3)
• EPA Substance Registry System: N-tert-butyoxycarbonyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester(112896-94-3)

Safety Data

• Hazardous Substances Data: 112896-94-3(Hazardous Substances Data)

Upstream product

• 112896-91-0 (S)-N-tert-butoxycarbonyl-4-tert-butyldimethylsilyloxy-α-diazoacetylbenzylamine 
• 112896-87-4 methyl (R)-3-<1-(tert-butyldimethylsilyl)indol-3-yl>-2-(N-tert-butoxycarbonyl-N-methylamino)propanoate 
• 112896-92-1 N-tert-butoxycarbonyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 112896-90-9 N-tert-butoxycarbonyl-O-tert-butyldimethylsilyl-(S)-4-hydroxyphenylglycine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 112896-88-5 methyl (R)-3-(2-bromo-1H-indol-3-yl)-2-(N-tert-butoxycarbonyl-N-methylamino)-propanoate 
• 122747-97-1 methyl (R)-3-(1H-indol-3-yl)-2-(N-tert-butoxycarbonyl-N-methylamino)propanoate 
• 32462-30-9 (S)-hydroxyphenylglycine 
• 69651-48-5 N-tert-butyloxycarbonyl-L-4-hydroxyphenylglycine 
• 112896-89-6 N-tert-butoxycarbonyl-N-methyl-2-bromo-(R)-tryptophan 
• 112896-93-2 O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-but 

Downstream Products

• 112896-83-0 N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 119717-37-2 jasplakinolide 
• 161722-16-3 (S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 161722-17-4 N-tert-butoxycarbonyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 
• 161722-15-2 (2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine 
• 161722-19-6 (2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine ρ-lactone 
• 161722-18-5 (2S,4E,6R,8S)-8-tert-butyldimethylsilyloxy-2,4,6-trimethyl-4-nonenoyl-(S)-alanyl-N-methyl-2-bromo-(R)-tryptophanyl-O-tert-butyldimethylsilyl-(R)-β-tyrosine tert-butyl ester 

Relevant articles and documents

Studies on the Novel Cyclodepsipeptides. A Total Synthesis of (+)-Jasplakinolide (Jaspamide)

Diastereocontrolled total synthesis of (+)-jasplakinolide (1) has been accomplished via coupling of the tetrapropionate-derived segment (9) with the tripeptide (10) followed by trichlorobenzoyl chloride-mediated macrolactonization.