112904-73-1

Basic information

• Product Name: 2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY-
• Synonyms: 2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY-;(8-methoxy-3,4-dihydro-2H-chromen-3-yl)amine(SALTDATA: FREE);(8-Methoxy-3,4-dihydro-2H-chroMen-3-yl)aMine;(8-Methoxy-3,4-dihydro-2H-chromen-3-yl)amine hydrochloride;3,4-Dihydro-8-methoxy-2H-1-benzopyran-3-amine;(8-methoxychroman-3-yl)amine;8-methoxy-3-chromanamine;8-methoxychroman-3-amine
• CAS NO: 112904-73-1
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.22
• Mol File: 112904-73-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 203-205℃ (ethanol ethyl ether )
• Boiling Point: 299.3±40.0 °C(Predicted)
• Appearance: /
• Density: 1.128±0.06 g/cm3(Predicted)
• PKA: 7.91±0.20(Predicted)
• CAS DataBase Reference: 2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY-(112904-73-1)
• EPA Substance Registry System: 2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-8-METHOXY-(112904-73-1)

Safety Data

• Hazardous Substances Data: 112904-73-1(Hazardous Substances Data)

Usage

General Description

"2H-1-Benzopyran-3-amine, 3,4-dihydro-8-methoxy-" is a chemical compound that belongs to the family of benzopyrans, which are organic compounds containing a benzene ring fused to a pyran ring. The major characteristic of this particular compound is the methoxy group attached to the 8th carbon and an amine group attached to the 3rd carbon of the benzopyran structure. The properties of this compound can vary extensively, depending primarily on the nature of the group attached to the pyran ring. Its applications and uses are most commonly found in scientific research and the field of organic synthesis.

Upstream product

• 92210-59-8 8-methoxy-3-nitro-2H-1-benzopyran 
• 22406-62-8 3-amino-8-methoxy-3,4-dihydro-2H-1-benzopyran-4-one hydrochloride 
• 119284-77-4 3-acetamido-8-methoxy-4-chromanone 
• 119284-78-5 3-acetamido-8-methoxychroman 
• 137279-47-1 8-methoxy-3,4-dihydro-3-nitro-2H-1-benzopyran 

Downstream Products

• 112904-74-2 (-)-8-hydroxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran 
• 112904-74-2 (+)-8-hydroxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran 
• 112904-74-2 N,N-di-n-propyl-8-hydroxy-3-chromanamine 

Relevant articles and documents

ALPHA, BETA-UNSATURATED AMIDE COMPOUND

An object of the present invention is to provide an α,β-unsaturated amide compound or a pharmaceutically acceptable salt or the like thereof having anticancer activity and the like. The α,β-unsaturated amide compound represented by the following formula (I) or a pharmaceutically acceptable salt or the like thereof has anticancer activity and the like: [wherein, "A" represents optionally substituted heterocyclic diyl, R1 represents hydrogen atom or optionally substituted lower alkyl, R2 represents optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted aliphatic heterocyclic group or optionally substituted aromatic heterocyclic group, X represents -O-, -S-, -SO2-, -NRX1- (wherein, RX1 represents hydrogen atom or lower alkyl), -CHRX2- (wherein, RX2 represents hydrogen atom or hydroxy), -CH=CH-, -CO- or -NH-CO-, and n1 and n2 are the same or different, and each represents 0 or 1].

Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrans: New synthesis and dopaminergic activity

The synthesis of methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran from readily available or commercial o-hydroxybenzaldehydes is described in six steps. The enantiomers of 8-hydroxy-3,4-dihydro-3-(di-n-propyl-amino)-2H-1-benzopyran 1b have been resolved. It is shown that the compound (-)-1b is a mroe selective D-2 agonist, compared to apomorphine.